From the Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Clin Nucl Med. 2023 Oct 1;48(10):e468-e469. doi: 10.1097/RLU.0000000000004788. Epub 2023 Aug 3.
18 F-FDG uptake in radiation pneumonitis is well documented; however, the same is less so for 18 F-floroestradiol (FES), which specifically binds to the estrogen receptors in vivo. We observed increased FES uptake in the right lung of an estrogen receptor positive breast cancer patient who had undergone right modified radical mastectomy followed by radiation therapy to chest wall. The possibility of FES uptake in radiation pneumonitis must therefore be kept in mind while interpreting FES PET.
18 F-FDG 在放射性肺炎中的摄取已有充分的文献记载；然而，18 F-氟雌二醇（FES）的情况则较少，因为它专门在体内与雌激素受体结合。我们观察到一位雌激素受体阳性的乳腺癌患者在接受右改良根治性乳房切除术和胸部放射治疗后，其右肺的 FES 摄取增加。因此，在解释 FES PET 时，必须考虑到 FES 在放射性肺炎中的摄取。
