School of Chemical and Biological Engineering, Seoul National University, Seoul 151-744, Korea.
Adv Healthc Mater. 2014 Feb;3(2):176-81. doi: 10.1002/adhm.201300177. Epub 2013 Aug 15.
The potential of graphene as a mesenchymal stem cell (MSC) culture substrate to promote cardiomyogenic differentiation is demonstrated. Graphene exhibits no sign of cytotoxicity for stem cell culture. MSCs are committed toward cardiomyogenic lineage by simply culturing them on graphene. This may be attributed, at least partially, to the regulation of expression levels of extracellular matrix and signaling molecules.
研究表明，石墨烯作为间充质干细胞（MSC）培养底物具有促进心肌生成分化的潜力。石墨烯对干细胞培养没有表现出任何细胞毒性的迹象。通过简单地在石墨烯上培养 MSC，即可使它们向心肌生成谱系分化。这至少部分归因于细胞外基质和信号分子表达水平的调节。
