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石墨烯及其杂化纳米复合材料:组织工程领域的一次蜕变提升。

Graphene and its hybrid nanocomposite: A Metamorphoses elevation in the field of tissue engineering.

作者信息

Singh Rajesh, Rawat Hemant, Kumar Ashwani, Gandhi Yashika, Kumar Vijay, Mishra Sujeet K, Narasimhaji Ch Venkata

机构信息

Department of Chemistry, Central Ayurveda Research Institute Jhansi, U.P, 284003, India.

Department of Heterogeneous Catalysis, Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, 45470, Mülheim an der Ruhr, Germany.

出版信息

Heliyon. 2024 Jun 25;10(13):e33542. doi: 10.1016/j.heliyon.2024.e33542. eCollection 2024 Jul 15.

DOI:10.1016/j.heliyon.2024.e33542
PMID:39040352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11261797/
Abstract

In this discourse, we delve into the manifold applications of graphene-based nanomaterials (GBNs) in the realm of biomedicine. Graphene, characterized by its two-dimensional planar structure, superconductivity, mechanical robustness, chemical inertness, extensive surface area, and propitious biocompatibility, stands as an exemplary candidate for diverse biomedical utility. Graphene include various distinctive characteristics of its two-dimensional planar structure, enormous surface area, mechanical and chemical stability, high conductivity, and exceptional biocompatibility. We investigate graphene and its diverse derivatives, which include reduced graphene oxides (rGOs), graphene oxides (GOs), and graphene composites, with a focus on elucidating the unique attributes relevant to their biomedical utility. In this review article it highlighted the unique properties of graphene, synthesis methods of graphene and functionalization methods of graphene. In the quest for novel materials to advance regenerative medicine, researchers have increasingly turned their attention to graphene-based materials, which have emerged as a prominent innovation in recent years. Notably, it highlights their applications in the regeneration of various tissues, including nerves, skeletal muscle, bones, skin, cardiac tissue, cartilage, and adipose tissue, as well as their influence on induced pluripotent stem cells, marking significant breakthroughs in the field of regenerative medicine. Additionally, this review article explores future prospects in this evolving area of study.

摘要

在本论述中,我们深入探讨基于石墨烯的纳米材料(GBNs)在生物医学领域的多种应用。石墨烯具有二维平面结构、超导性、机械强度高、化学惰性、表面积大以及良好的生物相容性等特点,是多种生物医学应用的理想候选材料。石墨烯具有二维平面结构、巨大表面积、机械和化学稳定性、高导电性以及卓越生物相容性等多种独特特性。我们研究石墨烯及其各种衍生物,包括还原氧化石墨烯(rGOs)、氧化石墨烯(GOs)和石墨烯复合材料,重点阐明与它们生物医学应用相关的独特属性。在这篇综述文章中,突出了石墨烯的独特性质、石墨烯的合成方法以及石墨烯的功能化方法。在寻求推进再生医学的新型材料过程中,研究人员越来越关注基于石墨烯的材料,这些材料近年来已成为一项突出的创新成果。值得注意的是,它突出了它们在各种组织再生中的应用,包括神经、骨骼肌、骨骼、皮肤、心脏组织、软骨和脂肪组织,以及它们对诱导多能干细胞的影响,标志着再生医学领域的重大突破。此外,这篇综述文章还探讨了这一不断发展的研究领域的未来前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f1/11261797/b00f7116cbda/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f1/11261797/db1586ac47f0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f1/11261797/7ded7b64af46/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f1/11261797/464ff40d1e70/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f1/11261797/7ccba23dfc56/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f1/11261797/b00f7116cbda/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f1/11261797/db1586ac47f0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f1/11261797/7ded7b64af46/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f1/11261797/464ff40d1e70/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f1/11261797/7ccba23dfc56/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1f1/11261797/b00f7116cbda/gr5.jpg

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