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[高血压及肾性症状性高血压患者红细胞膜钠/氢代谢率的差异]

[Differences in metabolic rate of Na+/H+ in the erythrocyte membrane in hypertension and symptomatic hypertension of renal origin].

作者信息

Postnov I Iu, Liusov V A, Kukharenko V Iu

出版信息

Kardiologiia. 1990 Apr;30(4):80-2.

PMID:2395271
Abstract

Na+/H+ turnover rate in the erythrocyte membranes were measured in 20 patients with Stages II and III essential hypertension, 11 patients with renal hypertension and 10 healthy subjects. The patients with essential hypertension showed a two-fold increase in Na+/H+ turnover rate as compared to the controls. Those with renal hypertension displayed no changes in the rate. The rate of Na+/H+ turnover was not associated with the patients' sex and was the same in Stages II and III essential hypertension. Measuring the Na+/H+ exchange rate was proposed to be an additional diagnostic tool for the differential diagnosis of arterial hypertension.

摘要

对20例II期和III期原发性高血压患者、11例肾性高血压患者和10名健康受试者的红细胞膜Na⁺/H⁺周转率进行了测量。与对照组相比,原发性高血压患者的Na⁺/H⁺周转率增加了两倍。肾性高血压患者的该比率没有变化。Na⁺/H⁺周转率与患者性别无关,在II期和III期原发性高血压患者中相同。测量Na⁺/H⁺交换率被提议作为动脉高血压鉴别诊断的一种辅助诊断工具。

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