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采用扫描成像 X 射线显微镜光学元件的三维相衬 X 射线显微断层摄影术。

Three-dimensional phase-contrast X-ray microtomography with scanning-imaging X-ray microscope optics.

机构信息

Research and Utilization Division, Japan Synchrotron Radiation Research Institute, 1-1-1 Kouto, Sayo, Sayo-gun, Hyogo 679-5198, Japan.

出版信息

J Synchrotron Radiat. 2013 Sep;20(Pt 5):793-800. doi: 10.1107/S0909049513018876. Epub 2013 Jul 26.

Abstract

A three-dimensional (3D) X-ray tomographic micro-imaging system has been developed. The optical system is based on a scanning-imaging X-ray microscope (SIXM) optics, which is a hybrid system consisting of a scanning microscope optics with a one-dimensional (1D) focusing (line-focusing) device and an imaging microscope optics with a 1D objective. In the SIXM system, each 1D dataset of a two-dimensional (2D) image is recorded independently. An object is illuminated with a line-focused beam. Positional information of the region illuminated by the line-focused beam is recorded with the 1D imaging microscope optics as line-profile data. By scanning the object with the line focus, 2D image data are obtained. In the same manner as for a scanning microscope optics with a multi-pixel detector, imaging modes such as phase contrast and absorption contrast can be arbitrarily configured after the image data acquisition. By combining a tomographic scan method and the SIXM system, quantitative 3D imaging is performed. Results of a feasibility study of the SIXM for 3D imaging are shown.

摘要

已开发出一种三维(3D)X 射线断层扫描微成像系统。该光学系统基于扫描成像 X 射线显微镜(SIXM)光学系统,它是一种混合系统,由具有一维(1D)聚焦(线聚焦)装置的扫描显微镜光学系统和具有 1D 物镜的成像显微镜光学系统组成。在 SIXM 系统中,二维(2D)图像的每个 1D 数据集都是独立记录的。用线聚焦光束照射物体。用 1D 成像显微镜光学系统记录线聚焦光束照射的区域的位置信息作为线轮廓数据。通过用线焦点扫描物体,获得 2D 图像数据。与具有多像素探测器的扫描显微镜光学系统一样,可以在图像数据采集后任意配置相衬和吸收衬度等成像模式。通过结合层析扫描方法和 SIXM 系统,可以进行定量 3D 成像。展示了 SIXM 进行 3D 成像的可行性研究结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6fe/4032070/72facbe80be0/s-20-00793-fig1.jpg

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