South London Maudsely NHS Foundation Trust, Anxiety Disorders Residential Unit, Bethlem Royal Hospital, Monks Orchard Road, London, BR3 3BX, UK,
Soc Psychiatry Psychiatr Epidemiol. 2014 Mar;49(3):359-66. doi: 10.1007/s00127-013-0754-3. Epub 2013 Aug 17.
To investigate social support and network features in people with first-episode psychosis, and to examine anxiety as a possible mediator between loneliness and a rating of paranoia.
Thirty-eight people with first-episode psychosis were recruited for a cross-sectional study. Self-report questionnaires and structured interviews assessed symptoms, functioning, and qualitative social network and support features. A mood-induction task involved watching anxiety-inducing pictures on a computer screen. Visual analogue scales assessed changes in paranoia, anxiety and loneliness and a mediation analysis was conducted.
One-third of the sample (34%) had no confidant [95% CI (18.4, 50.0%)]. The average number of weekly contacts was 3.9, with 2.6 lonely days. Poor perceived social support, loneliness and the absence of a confidant were strongly associated with psychosis and depressive symptoms (0.35 < rs < 0.60). The association between loneliness and paranoia was mediated through anxiety (ab = 0.43, z = 3.5; p < 0.001).
Even at first episode, a large proportion of people with psychosis have poor perceived support, no confidant and report several lonely days a week. Patients without a confidant appear to be more susceptible to feeling lonely and anxious. Anxiety may be one pathway through which loneliness affects psychosis. Interventions which focus on this are indicated.
调查首发精神病患者的社会支持和网络特征,并探讨焦虑是否可能在孤独感与偏执感评分之间起中介作用。
本横断面研究招募了 38 名首发精神病患者。采用自报式问卷和结构访谈评估症状、功能以及定性社会网络和支持特征。采用观看电脑屏幕上的焦虑诱发图片的情绪诱导任务,使用视觉模拟量表评估偏执感、焦虑和孤独感的变化,并进行中介分析。
三分之一的患者(34%)没有知己[95%可信区间(18.4,50.0%)]。每周的平均联系次数为 3.9 次,孤独日为 2.6 天。较差的感知社会支持、孤独感和没有知己与精神病和抑郁症状强烈相关(0.35<rs<0.60)。孤独感与偏执感之间的关联通过焦虑起中介作用(ab=0.43,z=3.5;p<0.001)。
即使在首发期,很大一部分精神病患者的感知支持较差,没有知己,每周报告有几天感到孤独。没有知己的患者似乎更容易感到孤独和焦虑。焦虑可能是孤独感影响精神病的一种途径。表明需要进行针对这一途径的干预。