J Biomed Opt. 2013 Aug;18(8):80503. doi: 10.1117/1.JBO.18.8.080503.
A new approach to retrieve the attenuation-corrected fluorescence using spatial frequency-domain imaging is demonstrated. Both in vitro and ex vivo experiments showed the technique can compensate for the fluorescence attenuation from tissue absorption and scattering. This approach has potential in molecular image-guided surgery.
本文提出了一种利用空间频域成像技术获取荧光衰减校正的新方法。离体和在体实验均表明,该技术可以补偿组织吸收和散射引起的荧光衰减。该方法在分子影像引导手术中有很大的应用潜力。