Chan Fang-Tse, Chang Geng-Ruei, Wang Hsien-Chi, Hsu Tien-Huan
Department of Veterinary Medicine, National Chung Hsing University, 250 Kuo-Kuang Road, Taichung, Taiwan 402, R.O.C.
J Vet Med Sci. 2013 Dec 30;75(12):1591-600. doi: 10.1292/jvms.13-0161. Epub 2013 Aug 13.
The initial goal of this study was to determine the minimum anesthetic concentration (MAC) for isoflurane (ISO) and sevoflurane (SEVO) for the crested serpent eagle. Next, we compared the anesthetic effects of each on the physiological effects, hematocrit, plasma chemistry values and behavior in spontaneously breathing captive adult crested serpent eagles. Sixteen eagles were randomly allocated to two groups for anesthesia with ISO (n=8) or SEVO (n=8). First, we measured the MAC values of ISO and SEVO, and four weeks later, we investigated the effect of each on the physiological effects, hematocrit (HCT) and plasma chemistry values. The MAC values of ISO and SEVO for crested serpent eagles were 1.46 ± 0.30 and 2.03 ± 0.32%, respectively. The results revealed no significant differences between the two anesthetics in induction time, while time of extubation to recovery was significantly shorter with SEVO. A time-related increase in end-tidal CO₂ and decreases in body temperature and respiratory rates were observed during anesthesia with each anesthetic. There were no significant differences between the effect of the two anesthetics on heart rate, hematocrit, plasma chemistry values or respiration, although each caused minor respiration depression. We concluded that SEVO is a more effective inhalant agent than ISO for use in eagles, showing the most rapidest induction and recovery from anesthesia.
本研究的初始目标是确定凤头鹰对异氟烷(ISO)和七氟烷(SEVO)的最低麻醉浓度(MAC)。接下来,我们比较了二者对自主呼吸的圈养成年凤头鹰的生理效应、血细胞比容、血浆化学值和行为的麻醉效果。16只鹰被随机分为两组,分别用ISO(n = 8)或SEVO(n = 8)进行麻醉。首先,我们测量了ISO和SEVO的MAC值,四周后,我们研究了二者对生理效应、血细胞比容(HCT)和血浆化学值的影响。凤头鹰对ISO和SEVO的MAC值分别为1.46±0.30%和2.03±0.32%。结果显示,两种麻醉剂在诱导时间上无显著差异,而SEVO的拔管至恢复时间明显更短。在使用每种麻醉剂麻醉期间,观察到呼气末二氧化碳随时间增加,体温和呼吸频率下降。两种麻醉剂对心率、血细胞比容、血浆化学值或呼吸的影响无显著差异,尽管每种麻醉剂都引起了轻微的呼吸抑制。我们得出结论,对于鹰类,SEVO是比ISO更有效的吸入麻醉剂,其麻醉诱导和恢复最为迅速。