Deori Parag, Sarma Kushal Konwar, Nath Parsha Jyoti, Singh Chandan Kumar, Nath Rita
Department of Surgery and Radiology, College of Veterinary Science, Assam Agricultural University, Khanapara Campus, Guwahati, Assam, India.
Department of Veterinary Biochemistry, College of Veterinary Science, Assam Agricultural University, Khanapara Campus, Guwahati, Assam, India.
Vet World. 2017 May;10(5):493-497. doi: 10.14202/vetworld.2017.493-497. Epub 2017 May 8.
Aim of the study was to evaluate the effect of isoflurane anesthesia on physiological parameters, assessment of anesthetic qualities, and economy of use of isoflurane in domestic chickens ().
In this study, 18 apparently healthy adult domestic chickens were selected randomly and divided into three groups. The birds were anesthetized by masked induction with isoflurane at a dose rate of 3.5%, 4%, and 5% and were maintained with 1.5%, 2%, and 2.5% isoflurane with oxygen by endotracheal intubation in Groups I, II, and III, respectively. Physiological parameters, viz., cloacal temperature, heart rate, and respiration rate were recorded at 0, 5, 10, 20, 30, 40, 50, and 60 min. The quality of anesthesia was assessed on the basis of induction time, induction behavior, quality of sedation, production of analgesia, degree of muscle relaxation, palpebral reflex, recovery time, and recovery behavior. The economy of anesthesia was calculated in terms of quantity of isoflurane utilized during 60 min of study. Statistical analysis was performed by analysis of variance, Duncan's multiple range tests.
There was significant decrease (p<0.01) in physiological parameters such as in cloacal temperature, heart rate and respiration rate in the birds of all the groups from 0 to 60 min. The induction time was 5.83±0.33, 2.37±0.18, and 0.87±0.15 min, respectively, in Groups I, II, and III. Induction behavior was smooth in Group III, whereas mildly stormy in Group II and I. Quality of sedation was excellent in Group III, better in Group II as compared to Group I. Analgesia was moderate in Group III whereas poor in Group II and I. Degree of muscle relaxation was excellent in Group III, whereas good in Group I and II. Palpebral reflexes were absent in all the groups. Recovery time was 15.33±0.84, 18.83±0.94, and 26.50±0.85 in Groups I, II, and III respectively. Recovery behavior was smooth in birds of all the groups. The cost of the anesthesia was 158.22±1.04, 194.27±0.66, and 236.84±0.60 Indian National Rupee in Groups I, II, and III, respectively. Quantity of anesthesia utilized in each group was 7.62±0.05, 9.35±0.03, and 11.41±0.03 ml in Groups I, II, and III, respectively.
The use of isoflurane at different concentration produces different level of physiological changes, quality of anesthesia and economy without causing any deleterious effect on the birds. The physiological parameters observed in this study can serve as reference values for the wild and endangered birds.
本研究旨在评估异氟烷麻醉对家鸡生理参数的影响、麻醉质量评估以及异氟烷在家鸡中的使用经济性。
本研究随机选取18只外观健康的成年家鸡，分为三组。分别对三组家鸡采用面罩诱导麻醉，第一组、第二组和第三组异氟烷剂量率分别为3.5%、4%和5%，随后通过气管插管分别用1.5%、2%和2.5%的异氟烷与氧气维持麻醉。在0、5、10、20、30、40、50和60分钟记录生理参数，即泄殖腔温度、心率和呼吸频率。根据诱导时间、诱导行为、镇静质量、镇痛效果、肌肉松弛程度、眼睑反射、恢复时间和恢复行为评估麻醉质量。根据研究60分钟内使用的异氟烷量计算麻醉经济性。采用方差分析、邓肯多重极差检验进行统计分析。
所有组家鸡从0到60分钟，泄殖腔温度、心率和呼吸频率等生理参数均显著下降（p<0.01）。第一组、第二组和第三组的诱导时间分别为5.83±0.33、2.37±0.18和0.87±0.15分钟。第三组诱导行为平稳，而第二组和第一组轻度剧烈。第三组镇静质量极佳，第二组优于第一组。第三组镇痛效果中等，而第二组和第一组较差。第三组肌肉松弛程度极佳，而第一组和第二组良好。所有组均无眼睑反射。第一组、第二组和第三组的恢复时间分别为15.33±0.84、18.83±0.94和26.50±0.85分钟。所有组家鸡恢复行为平稳。第一组、第二组和第三组麻醉费用分别为158.22±1.04、194.27±0.66和236.84±0.60印度卢比。第一组、第二组和第三组每组使用的麻醉量分别为7.62±0.05、9.35±0.03和11.41±0.03毫升。
使用不同浓度的异氟烷会产生不同程度的生理变化、麻醉质量和经济性，且对家鸡无任何有害影响。本研究中观察到的生理参数可为野生和濒危鸟类提供参考值。
