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异氟烷和七氟烷在禽类患者中的比较评估。

Comparative evaluation of isoflurane and sevoflurane in avian patients.

作者信息

Anjana R R, Parikh P V, Mahla J K, Kelawala D N, Patel K P, Ashwath S N

机构信息

Department of Veterinary Surgery and Radiology, Anand Agricultural University, Anand, Gujarat, India.

出版信息

Vet World. 2021 May;14(5):1067-1073. doi: 10.14202/vetworld.2021.1067-1073. Epub 2021 May 4.

Abstract

BACKGROUND AND AIM

Literature comparing the use of isoflurane and sevoflurane inhalation anesthetic agents in birds is scarce. This study aimed to evaluate the comparison of isoflurane and sevoflurane during induction, maintenance, and recovery of anesthesia in avian patients.

MATERIALS AND METHODS

In this study, 24 injured avian patients (n=24) were selected randomly and divided into four groups during kite flying festival. In the present study, isoflurane and sevoflurane were used as induction and maintenance anesthetic agents, with and without butorphanol tartrate premedication agent in all the birds. Different physiological parameters were evaluated, namely, cloacal temperature (°F), heart rate (beats/min), respiratory rate (breaths/min), and SpO (%) were recorded at 0, 10, 20 min, and at recovery time. The quality of anesthesia was assessed on the basis of induction time, quality of induction, production of analgesia, muscle relaxation, body reflexes, recovery time, quality of recovery, sitting, standing, and complete recovery time (CRT).

RESULTS

The mean±standard error value of induction time was 230.00±32.55, 280.00±25.29, 180.00±21.90, and 260.00±36.87 s, respectively, in Groups I, II, III, and IV. The feather plucking, pharyngeal, and toe pinching reflexes were noticed, when the birds were passing through the light plane of anesthesia during induction. Comparison of cloacal temperature at the time of recovery between Group-I versus Group-III revealed a significant difference (p<0.05). Comparison of mean respiratory rates at the time of recovery between Group-II versus Group-IV revealed a significant difference (p<0.05). Excellent quality of recovery was observed in all the groups of anesthetic protocols. Sitting, standing, and CRT were observed shortest in avian patients maintained with sevoflurane as compared to isoflurane.

CONCLUSION

The quality of induction of anesthesia was rapid in avian patients when induced with sevoflurane as compared to isoflurane. Rapid onset of induction and recovery of anesthesia were found with sevoflurane followed by isoflurane. Induction and maintenance of anesthesia in avian patients with sevoflurane resulted in the lowest time required for sitting, standing, and CRT.

摘要

背景与目的

关于比较异氟烷和七氟烷吸入麻醉剂在鸟类中使用情况的文献较少。本研究旨在评估异氟烷和七氟烷在鸟类患者麻醉诱导、维持及苏醒过程中的差异。

材料与方法

在本研究中,24只受伤鸟类患者(n = 24)在风筝节期间被随机选取并分为四组。在本研究中,异氟烷和七氟烷被用作诱导和维持麻醉剂,所有鸟类均使用或不使用酒石酸布托啡诺作为术前用药。评估了不同的生理参数,即泄殖腔温度(°F)、心率(次/分钟)、呼吸频率(次/分钟)以及血氧饱和度(%),分别在0、10、20分钟及苏醒时进行记录。根据诱导时间、诱导质量、镇痛效果、肌肉松弛程度、身体反射、苏醒时间、苏醒质量、坐立、站立及完全苏醒时间(CRT)来评估麻醉质量。

结果

第一、二、三、四组的诱导时间平均±标准误值分别为230.00±32.55、280.00±25.29、180.00±21.90及260.00±36.87秒。在诱导过程中,当鸟类经过浅麻醉平面时,可观察到拔羽、咽及脚趾夹捏反射。第一组与第三组苏醒时泄殖腔温度的比较显示出显著差异(p < 0.05)。第二组与第四组苏醒时平均呼吸频率的比较显示出显著差异(p < 0.05)。在所有麻醉方案组中均观察到了良好的苏醒质量。与异氟烷相比,使用七氟烷维持麻醉的鸟类患者坐立、站立及CRT时间最短。

结论

与异氟烷相比,七氟烷诱导鸟类患者麻醉时诱导质量更快。七氟烷麻醉诱导和苏醒起效迅速,其次是异氟烷。使用七氟烷对鸟类患者进行麻醉诱导和维持,坐立、站立及CRT所需时间最短。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8138/8243694/04d0318d564c/Vetworld-14-1067-g001.jpg

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