免疫动物白细胞产生干扰素的两种机制。
Two mechanisms of interferon production by leukocytes from immunized animals.
作者信息
Trubina L M, Yakovenko Z F, Zakharchenko E M, Lychkovskaya E V
出版信息
Acta Virol. 1975 Apr;19(2):116-20.
Leukocytes from animals immunized against measles were treated with different doses of interferon and 5-fluorouracil. Under the influence of virus-inducer, two mechanisms of interferon production were realized in the leukocytes: early after immunization (1 day), pre-existing interferon was released; subsequently (4 days) de novo interferon production was started. Interferons induced in cultures of leukocytes from animals at 1 and 4 days after immunization were shown to differ in some physico-chemical properties.
用不同剂量的干扰素和5-氟尿嘧啶处理针对麻疹免疫动物的白细胞。在病毒诱导剂的影响下，白细胞中实现了两种干扰素产生机制：免疫后早期（1天），预先存在的干扰素被释放；随后（4天）开始从头产生干扰素。结果显示，免疫后1天和4天从动物白细胞培养物中诱导产生的干扰素在某些物理化学性质上有所不同。
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