帕利夫明对BEAM方案后异基因造血干细胞移植受者肠道黏膜炎的影响。
Impact of palifermin on intestinal mucositis of HSCT recipients after BEAM.
作者信息
Herbers A H E, van der Velden W J F M, de Haan A F J, Donnelly J P, Blijlevens N M A
机构信息
Department of Haematology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Department of Health Evidence, Nijmegen Institute for Infection, Inflammation and Immunity (N4i), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
出版信息
Bone Marrow Transplant. 2014 Jan;49(1):8-10. doi: 10.1038/bmt.2013.118. Epub 2013 Aug 19.
PMID:23955637
Abstract
The matched-control study failed to show a clinical relevant impact of palifermin on intestinal mucositis, although there was a reduced inflammatory response and less febrile neutropenia among patients who had no bacteraemia.
摘要
配对对照研究未能显示帕利夫明对肠道黏膜炎有临床相关影响，尽管在无菌血症的患者中炎症反应有所减轻且发热性中性粒细胞减少情况较少。
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