冠状病毒OC 43株的生物物理特性。
Biophysical properties of coronavirus strain OC 43.
作者信息
Pokorný J, Brůcková M, Rýc M
出版信息
Acta Virol. 1975 Apr;19(2):137-42.
PMID:239559
Abstract
Coronavirus OC 43 from suckling mouse brains was subjected to sucrose density gradient centrifugation. Maxima of complement fixing (CF) activities occurred in the ribosomal (density 1.14) and mitochondrial (density 1.19) fraction which contained incomplete, damaged virus particles. The haemagglutinating (HA) activity was associated with the microsomal soluble protein fraction displayed no antigenic activity. The isolated purified virus proved to be very unstable.
摘要
对来自乳鼠脑的冠状病毒OC 43进行蔗糖密度梯度离心。补体结合（CF）活性最大值出现在核糖体（密度1.14）和线粒体（密度1.19）组分中，这些组分含有不完整、受损的病毒颗粒。血凝（HA）活性与微粒体可溶性蛋白组分相关，但无抗原活性。分离纯化的病毒被证明非常不稳定。
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