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高海拔模拟氦氧潜水对血细胞、肝功能和肾功能的影响。

Effects of simulated heliox diving at high altitudes on blood cells, liver functions and renal functions.

作者信息

Hu Hui-Jun, Fan Dan-Feng, Lv Yan, Zhang Yu, Yang Chen, Zhao Ling, Zhao Ru-Gang, Pan Xiao-Wen

机构信息

Department of Hyperbaric Oxygen, Navy General Hospital, Beijing, PR China.

出版信息

Undersea Hyperb Med. 2013 Jul-Aug;40(4):329-37.

Abstract

The aim of the present study was to examine the effects of simulated heliox diving at high altitudes on divers' blood cells, liver functions and renal functions. In this experiment, four divers lived for nine consecutive days in a dual-function high-low pressure chamber, which simulated air pressure at an altitude of 3,000 meters and at a 30-meter depth; an altitude of 4,000 meters and 30-meter depth; and at an altitude of 5,200 meters and 30 meters and 50 meters in depth. Total time underwater was 60 minutes. The subjects breathed heliox (with oxygen at 40% and helium at 60%) during the simulated 30-meter dive from zero altitude to 30 meters and while remaining underwater; they breathed air while ascending from 30 meters to 18. They breathed heliox (with oxygen at 26.7% and helium at 73.3%) in the simulated dive from zero altitude to 50 meters underwater, in remaining underwater and in ascending from 50 meters to 29; air while ascending from 29 meters to 18. Pure oxygen was breathed while ascending from 18 meters to the surface; then air. Results indicated: (1) the correlating indices of routine blood, liver and renal functions, and urine routine were all within normal reference ranges; and (2) the indices tested at other periods of time were not significantly different (p > 0.05) from the results at zero-meter level and 3,000-meter level. The study suggests that the heliox diving processes at different high altitudes simulated in this experiment have no significant impact upon divers' blood routine, liver functions and renal functions.

摘要

本研究的目的是检验高海拔模拟氦氧混合气潜水对潜水员血细胞、肝功能和肾功能的影响。在本实验中,四名潜水员在一个具有高低压双重功能的舱室内连续生活九天,该舱室模拟海拔3000米、深度30米处的气压;海拔4000米、深度30米处的气压;以及海拔5200米、深度30米和50米处的气压。水下总时长为60分钟。在从海拔零米至30米的模拟30米潜水过程中以及在水下停留时,受试者呼吸氦氧混合气(氧气占40%,氦气占60%);从30米上升至18米时呼吸空气。在从海拔零米至水下50米的模拟潜水中、在水下停留时以及从50米上升至29米时,他们呼吸氦氧混合气(氧气占26.7%,氦气占73.3%);从29米上升至18米时呼吸空气。从18米上升至水面时呼吸纯氧;然后呼吸空气。结果表明:(1)血常规、肝功能、肾功能及尿常规的相关指标均在正常参考范围内;(2)在其他时间段测试的指标与零米水平和3000米水平时的结果相比无显著差异(p>0.05)。该研究表明,本实验模拟的不同高海拔氦氧混合气潜水过程对潜水员的血常规、肝功能和肾功能无显著影响。

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