Lee Hui-Chieh, Chen Yin-Shin, Kang Bor-Hwang, Wan Fan-Jong, Chang Lu-Peng, Huang Kun-Lun
Diving Medicine, Zuo-Ying Armed Forces General Hospital, Kaohsiung, ROC.
Chin J Physiol. 2009 Oct 31;52(5):295-8. doi: 10.4077/cjp.2009.amh042.
Deep sea diving might cause a tremendous physical or psychological stress to the divers. The present study aims to evaluate the stress response to a simulated wet dive in Navy divers. Nineteen Navy divers took part in this study when they were undergoing annual deep dive training. Ten divers were exposed to 190 feet of sea water (fsw) breathing compressed air on day 1 and to 250 fsw breathing helium-oxygen (Heliox) gas mixture on day 3. Another 9 divers were exposed to 220 fsw on day 1 and 285 fsw on day 3 breathing Heliox gas mixture. The bottom time ranged from 5 to 8 min, and then the standard U.S. Navy air and Heliox decompression tables were followed for surfacing. Predive levels of serum heat shock protein 72 (sHsp72) were 9.95 +/- 0.56 ng/ml, which were significantly higher than those in the control group (8.01 +/- 0.77 ng/ml). After simulating Heliox dive, the sHsp72 increased to 10.43 +/- 0.56 ng/ml, but this was not statistically significant. Our results demonstrated that the serum level of Hsp72 is higher in the Navy divers who underwent regular intensive exercise. However, it remains unknown whether this increase of stress protein is associated with the diving stress or exercise preconditioning in the Navy divers.
深海潜水可能会给潜水员带来巨大的身体或心理压力。本研究旨在评估海军潜水员对模拟湿式潜水的应激反应。19名海军潜水员在接受年度深潜训练时参与了本研究。10名潜水员在第1天暴露于190英尺海水（fsw）深度，呼吸压缩空气，在第3天暴露于250 fsw深度，呼吸氦氧（Heliox）混合气体。另外9名潜水员在第1天暴露于220 fsw深度，在第3天暴露于285 fsw深度，呼吸Heliox混合气体。水底停留时间为5至8分钟，然后按照美国海军标准空气和氦氧减压表进行上浮。潜水前血清热休克蛋白72（sHsp72）水平为9.95±0.56 ng/ml，显著高于对照组（8.01±0.77 ng/ml）。模拟氦氧潜水后，sHsp72增加至10.43±0.56 ng/ml，但无统计学意义。我们的结果表明，经常进行高强度训练的海军潜水员血清Hsp72水平较高。然而，这种应激蛋白的增加是否与海军潜水员的潜水应激或运动预处理有关仍不清楚。
