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原发性皮肤和转移性黑色素瘤的治疗。

Management of primary cutaneous and metastatic melanoma.

机构信息

Center for Melanoma, Massachusetts General Hospital, Boston, MA, USA.

出版信息

Semin Oncol Nurs. 2013 Aug;29(3):195-205. doi: 10.1016/j.soncn.2013.06.005.

Abstract

OBJECTIVES

To review the diagnosis, staging, and treatments (both standard and novel) for advanced melanoma and discuss the nursing role in the care of patients with melanoma.

DATA SOURCES

Published research and education articles, on-line journals, recent texts, and references from pertinent articles.

CONCLUSION

Most melanomas are diagnosed at early localized stages when surgery alone can be curative. For patients diagnosed with metastatic disease, treatment options have been limited and generally considered ineffective. Recent developments in tumor genetics and a greater understanding of the role of the immune system in cancer have translated to better treatments.

IMPLICATIONS FOR NURSING PRACTICE

Nurses play a key role in ensuring that patients with melanoma understand their diagnosis, treatment recommendations (including supportive care, palliative chemotherapy, immunotherapies), and participation in clinical trials.

摘要

目的

回顾晚期黑色素瘤的诊断、分期和治疗方法(包括标准治疗和新方法),并讨论护理在黑色素瘤患者护理中的作用。

资料来源

已发表的研究和教育文章、在线期刊、最新文本以及相关文章的参考文献。

结论

大多数黑色素瘤在早期局限性阶段被诊断出来,此时单独手术就可以治愈。对于被诊断患有转移性疾病的患者,治疗选择有限,通常被认为无效。肿瘤遗传学的最新进展和对免疫系统在癌症中的作用的更深入了解,已经转化为更好的治疗方法。

对护理实践的意义

护士在确保黑色素瘤患者了解其诊断、治疗建议(包括支持性护理、姑息化疗、免疫疗法)以及参与临床试验方面发挥着关键作用。

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