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钾摄入对代谢综合征的益处:第四次韩国国家健康和营养检查调查(KNHANES IV)。

Benefits of potassium intake on metabolic syndrome: The fourth Korean National Health and Nutrition Examination Survey (KNHANES IV).

机构信息

Jangseong Public Health Center, Jangseong-gun, South Korea.

出版信息

Atherosclerosis. 2013 Sep;230(1):80-5. doi: 10.1016/j.atherosclerosis.2013.06.025. Epub 2013 Jul 12.

DOI:10.1016/j.atherosclerosis.2013.06.025
PMID:23958257
Abstract

OBJECTIVE

Potassium intake may be associated with metabolic syndrome and its components, but there has been little evidence so far. We evaluated the association between the metabolic syndrome and potassium intake in the general population.

METHODS

Participants were 7542 adults (≥20 years of age) from the fourth Korean National Health and Nutrition Examination Survey (2007-2009), which is a cross-sectional survey of a nationally representative sample of the Korean population. Data were obtained from standardized questionnaires as well as physical and laboratory examination reports. The 24-h recall method was used for dietary assessment. Metabolic syndrome was defined based on the modified National Cholesterol Education Program-Adult Treatment Panel III criteria. Multivariable logistic regression was performed to estimate the odds of metabolic syndrome and its components across potassium intake quartiles.

RESULTS

After adjusting for various lifestyle and dietary confounders, subjects in the highest quartile of potassium intake had 39% lower odds for metabolic syndrome compared to those in the lowest quartile (adjusted odds ratio [aOR] = 0.61; 95% confidence interval [CI]: 0.42-0.89; p for trend: 0.013). This association was consistent for both sexes. Among the components of metabolic syndrome, potassium intake was inversely related to abdominal obesity and fasting hyperglycemia in multivariate analysis (p for trend = 0.049 and 0.010, respectively).

CONCLUSION

Our results reveal a significant inverse association between potassium intake and metabolic syndrome in adults. Further studies are required to confirm this association.

摘要

目的

钾的摄入量可能与代谢综合征及其组分有关,但目前证据有限。我们评估了一般人群中代谢综合征与钾摄入量之间的关系。

方法

参与者为 7542 名成年人(≥20 岁),来自第四次韩国国家健康和营养检查调查(2007-2009 年),这是一项针对韩国人口的全国代表性样本的横断面调查。数据来自标准化问卷以及身体和实验室检查报告。采用 24 小时回顾法进行饮食评估。代谢综合征的定义基于改良的美国国家胆固醇教育计划-成人治疗小组 III 标准。采用多变量逻辑回归来估计钾摄入量四分位组之间代谢综合征及其组分的比值比(OR)。

结果

在调整了各种生活方式和饮食混杂因素后,钾摄入量最高四分位组的代谢综合征发生风险比最低四分位组低 39%(校正 OR [aOR] = 0.61;95%置信区间 [CI]:0.42-0.89;趋势检验的 p 值:0.013)。这种关联在男性和女性中均一致。在代谢综合征的组分中,钾摄入量与腹部肥胖和空腹高血糖呈负相关,在多变量分析中(趋势检验的 p 值分别为 0.049 和 0.010)。

结论

我们的结果显示,成年人中钾摄入量与代谢综合征之间存在显著的负相关。需要进一步的研究来证实这种关联。

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