Zaïri F, Allaoui M, Thines L, Arikat A, Assaker R
Pôle de neurochirurgie, hôpital Roger-Salengro, CHU de Lille, rue Emile-Laine, 59037 Lille, France.
Neurochirurgie. 2013 Aug-Oct;59(4-5):171-7. doi: 10.1016/j.neuchi.2013.05.002. Epub 2013 Aug 16.
Transforaminal lumbar interbody fusion (TLIF) is an effective technique, which can achieve a fusion rate of up to 90%. The minimally invasive approach has become increasingly popular because it is able to minimize iatrogenic soft tissue and muscle injury. Although the minimally invasive TLIF technique has gained popularity, its effectiveness compared with open TLIF has yet to be established. The authors prospectively compared the outcomes of patients who underwent mini-open TLIF with patients who underwent open TLIF.
Between 2007 and 2008, 50 patients underwent TLIF for grade 1 spondylolisthesis; 25 mini-open TLIF and 25 open TLIF. The mean age in each group was 48years, and there was no statistically significant difference between the groups. Data were collected perioperatively. Pain and functional disability were measured using a visual analogue scale (VAS) and the Oswestry disability index (ODI) at 3months, 6months, 1year and 2years. In addition, foraminal and disc height were measured at the same intervals and the fusion was evaluated at 1year on CT-scan. Soft tissue damage was evaluated by measuring the serum myoglobin and creatine phosphokinase activity.
The mean VAS improved from 7 to 2.8 and the ODI decreased from 30/50 to 15/50 and fusion rate at 1 year was 98%. There was no statistical difference for the clinical and radiological outcomes between the groups. The mean operative time was 186min for the open group, 170min for the mini-open group (P<0.05) and the mean blood loss was 486mL for the open group and 148mL for the mini-open group (P<0.01).
The mini-open TLIF procedure for symptomatic low grade spondylolisthesis is an effective option which achieves similar clinical and radiological outcomes and reduces perioperative morbidity as well as soft tissue damage.
经椎间孔腰椎椎间融合术(TLIF)是一种有效的技术,融合率可达90%。微创入路因其能将医源性软组织和肌肉损伤降至最低而越来越受欢迎。尽管微创TLIF技术已得到广泛应用,但其与开放TLIF相比的有效性尚未确定。作者前瞻性地比较了接受微创开放TLIF患者与接受开放TLIF患者的治疗结果。
2007年至2008年期间,50例患者因Ⅰ度腰椎滑脱接受TLIF治疗;25例行微创开放TLIF,25例行开放TLIF。每组的平均年龄为48岁,两组之间无统计学显著差异。围手术期收集数据。使用视觉模拟量表(VAS)和Oswestry功能障碍指数(ODI)在3个月、6个月、1年和2年时测量疼痛和功能障碍。此外,在相同时间间隔测量椎间孔和椎间盘高度,并在1年时通过CT扫描评估融合情况。通过测量血清肌红蛋白和肌酸磷酸激酶活性评估软组织损伤。
平均VAS从7改善至2.8,ODI从30/50降至15/50,1年时的融合率为98%。两组之间的临床和影像学结果无统计学差异。开放组的平均手术时间为186分钟,微创开放组为170分钟(P<0.05);开放组的平均失血量为486毫升,微创开放组为148毫升(P<0.01)。
对于有症状的低度腰椎滑脱,微创开放TLIF手术是一种有效的选择,可实现相似的临床和影像学结果,并减少围手术期发病率以及软组织损伤。