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耐甲氧西林金黄色葡萄球菌感染

Methicillin-resistant Staphylococcus aureus infections.

作者信息

Taylor Abraham R

机构信息

Department of Family and Community Medicine, Penn State Milton S. Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA.

出版信息

Prim Care. 2013 Sep;40(3):637-54. doi: 10.1016/j.pop.2013.06.002. Epub 2013 Jul 16.

DOI:10.1016/j.pop.2013.06.002
PMID:23958361
Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is an increasingly common multidrug-resistant clinical pathogen responsible for increasing health costs and for patient morbidity and mortality. Presented in this review, the definition, cell and molecular biology, epidemiology, prevention, diagnosis, and treatment of MRSA infections, including skin and soft tissue infections, bacteremia and endocarditis, pneumonia, bone and joint infections, and central nervous system infections, are addressed. In the treatment of MRSA, this article highlights several common antibiotics that retain activity against different strains of MRSA.

摘要

耐甲氧西林金黄色葡萄球菌(MRSA)是一种日益常见的多重耐药临床病原体,导致医疗成本增加以及患者发病和死亡。本综述介绍了MRSA感染的定义、细胞与分子生物学、流行病学、预防、诊断和治疗,包括皮肤和软组织感染、菌血症和心内膜炎、肺炎、骨和关节感染以及中枢神经系统感染。在MRSA的治疗方面,本文重点介绍了几种对不同菌株仍保持活性的常用抗生素。

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