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一例脉络膜黑色素瘤孤立性肺转移且无病生存期极长的病例。

A case of solitary pulmonary metastasis of choroidal melanoma with an exceptionally long disease-free period.

作者信息

Komatsu Teruya, Sowa Terumasa, Takahashi Koji, Fujinaga Takuji

机构信息

Department of General Thoracic Surgery, Nagara Medical Center, Gifu, Japan.

出版信息

Int J Surg Case Rep. 2013;4(10):849-51. doi: 10.1016/j.ijscr.2013.06.017. Epub 2013 Jul 16.

Abstract

INTRODUCTION

Choroidal melanoma is the most common primary malignant intraocular tumor in adults. And its metastatic spread has been considered to be hematogenous with the liver being the most common site, and a solitary pulmonary metastasis without hepatic involvement is quite rare.

PRESENTATION OF CASE

We report the case of a 61-year-old woman with a solitary pulmonary metastasis from choroidal melanoma, which had been originally treated with enucleation 13 years ago. Video-assisted thoracoscopic surgery (VATS) right upper lobectomy was performed for the right upper lobe tumor, which was histopathologically confirmed to be metastatic choroidal melanoma.

DISCUSSION

Our case is quite unusual in 2 points; firstly, a solitary pulmonary metastasis without hepatic involvement is rare. Secondly, this mode of metastasis with an exceptionally long disease-free period (13 years) is also rare.

CONCLUSION

A pulmonary metastasis from choroidal melanoma is described with reference to relevant literature.

摘要

引言

脉络膜黑色素瘤是成人最常见的原发性眼内恶性肿瘤。其转移扩散被认为是血行转移,肝脏是最常见的转移部位,而无肝脏受累的孤立性肺转移相当罕见。

病例介绍

我们报告一例61岁女性,患有脉络膜黑色素瘤的孤立性肺转移,该患者13年前最初接受了眼球摘除术。对右上叶肿瘤进行了电视辅助胸腔镜手术(VATS)右上叶切除术,病理组织学证实为转移性脉络膜黑色素瘤。

讨论

我们的病例在两点上非常不寻常;首先,无肝脏受累的孤立性肺转移很少见。其次,这种转移模式伴有异常长的无病生存期(13年)也很少见。

结论

结合相关文献描述了脉络膜黑色素瘤的肺转移。

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本文引用的文献

1
Choroidal melanoma.脉络膜黑色素瘤
Oman J Ophthalmol. 2012 Jan;5(1):3-9. doi: 10.4103/0974-620X.94718.
2
Uveal melanoma.葡萄膜黑色素瘤
J Skin Cancer. 2011;2011:573974. doi: 10.1155/2011/573974. Epub 2011 Jun 30.
7
Protracted survival after resection of metastatic uveal melanoma.转移性葡萄膜黑色素瘤切除术后的长期生存
Cancer. 2000 Oct 1;89(7):1561-8. doi: 10.1002/1097-0142(20001001)89:7<1561::aid-cncr21>3.0.co;2-r.

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