Guruvaiah Sridhara Nanditha, Guruvaiah Sridhara Namratha, Li Wengcheng, Ponnatapura Janardhana
St. George's University, School of Medicine, Saint George 00000, Grenada.
Department of Pathology, Wake Forest University Baptist Medical Center, Winston-Salem, NC, USA.
Radiol Case Rep. 2023 May 29;18(8):2653-2658. doi: 10.1016/j.radcr.2023.04.060. eCollection 2023 Aug.
Malignant melanoma is a highly aggressive cancer with metastatic potential to various locations such as the lymph nodes, lungs, liver, brain, and bone. After the lymph nodes, the lungs are the most common site of malignant melanoma metastases. Pulmonary metastases from malignant melanoma commonly presents as solitary or multiple solid nodules, sub-solid nodules or miliary opacities on CT chest. We present a case of pulmonary metastases from malignant melanoma in a 74-year-old man which presented unusually on CT chest as a combination of patterns like "crazy paving," upper lobe predominance with subpleural sparing, and centrilobular micronodules. Video-assisted thoracoscopic surgery, wedge resection and tissue analysis were performed, which confirmed the diagnosis of malignant melanoma metastases, and the patient further underwent PET-CT for staging and surveillance. Patients with pulmonary metastases from malignant melanoma can have atypical imaging findings, therefore radiologists should be aware of these unconventional presentations to avoid any misdiagnoses.
恶性黑色素瘤是一种具有高度侵袭性的癌症,有转移至淋巴结、肺、肝、脑和骨等不同部位的潜力。除淋巴结外,肺是恶性黑色素瘤转移最常见的部位。恶性黑色素瘤的肺转移在胸部CT上通常表现为单个或多个实性结节、亚实性结节或粟粒状阴影。我们报告一例74岁男性恶性黑色素瘤肺转移病例,其在胸部CT上表现异常,呈现出“铺路石征”、上叶为主且胸膜下 sparing以及小叶中心微结节等多种影像表现的组合。进行了电视辅助胸腔镜手术、楔形切除术和组织分析,确诊为恶性黑色素瘤转移,患者进一步接受PET-CT检查以进行分期和监测。恶性黑色素瘤肺转移患者可能有非典型的影像学表现,因此放射科医生应了解这些不常见的表现,以避免误诊。