Department of Chemical and Pharmaceutical Sciences, University of Trieste, 34127 Trieste, Italy.
Chem Commun (Camb). 2013 Oct 9;49(78):8794-6. doi: 10.1039/c3cc44572k.
Gold nanoparticles coated with fluorinated ligands (F-MPCs) present features suitable for (19)F MRI as observed from phantom experiments. Cellular uptake, by HeLa cells, and toxicity of fluorescent dye-decorated F-MPCs are presented together with their ability to bind hydrophobic molecules allowing for a potential combination of targeting, delivery and imaging features.
涂覆有氟化物配体的金纳米颗粒（F-MPCs）具有适合（19）F MRI 的特性，这一点从体模实验中可以观察到。本文展示了带荧光染料的 F-MPCs 的细胞摄取和毒性，以及它们与疏水分子结合的能力，这使其具有潜在的靶向、递药和成像特性的结合能力。
