J Gastrointest Surg. 2013 Nov;17(11):2025-7. doi: 10.1007/s11605-013-2310-6.
Sarcomatoid carcinoma is an uncommon biphasic malignant tumor of the stomach. The histogenesis remains unknown, and a definitive diagnosis is obtained with immunohistochemical staining. Since prognosis is poor after surgery, more effective diagnostic tools are needed in order to select the optimal therapeutic approach. We report the case of an old female patient presenting with an endophytic tumor in the gastric fundus who underwent partial resection of the stomach. Histology revealed a poorly differentiated adenocarcinoma component mixed with sarcomatoid component. Immunohistochemically, the carcinoma components exhibited a positive reaction to pan-cytokeratin, whereas fusiform cells showed positive reactions to vimentin.
梭形细胞癌是胃的一种罕见的双相恶性肿瘤。其组织发生尚不清楚，通过免疫组织化学染色可明确诊断。由于手术后预后较差，因此需要更有效的诊断工具来选择最佳的治疗方法。我们报告了一例老年女性患者，其胃底部有一个内生性肿瘤，行胃部分切除术。组织学显示低分化腺癌成分与梭形细胞癌成分混合存在。免疫组织化学染色显示，癌成分对广谱细胞角蛋白呈阳性反应，而梭形细胞呈波形蛋白阳性反应。
