丙泊酚和芬太尼联合作用引发心源性休克。
Additive effect of propofol and fentanyl precipitating cardiogenic shock.
作者信息
Prabhakaran Ac Jesudoss
机构信息
Department of Pharmacology, Meenakshi Medical College and Research Institute (Meenakshi University), Enathur, Kancheepuram, Tamil Nadu, India.
出版信息
J Pharmacol Pharmacother. 2013 Jul;4(3):217-9. doi: 10.4103/0976-500X.114612.
The intravenous administration of propofol and fentanyl has become a common practice in a variety of clinical settings including outpatient dermatologic, cosmetic and oral surgery. The combination provides both systematic sedation and analgesia with low incidence of unwanted side effects. The cardiogenic shock is very uncommon in healthy individuals. The cardiovascular depressive effect of propofol and fentanyl has been well established, but the development of cardiogenic shock is very rare when these drugs are used together. Hence the awareness of this effect is advantageous to the patients undergoing such surgeries.
在包括门诊皮肤科、美容和口腔手术在内的各种临床环境中，静脉注射丙泊酚和芬太尼已成为一种常见的做法。这种联合用药既能提供全身镇静又能镇痛，且不良反应发生率低。心源性休克在健康个体中非常罕见。丙泊酚和芬太尼的心血管抑制作用已得到充分证实，但当这两种药物一起使用时，心源性休克的发生非常罕见。因此，了解这种作用对接受此类手术的患者是有益的。
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