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澳大利亚急诊科的程序性镇静实践。

Procedural sedation practices in Australian Emergency Departments.

机构信息

Queen Elizabeth II Jubilee Hospital, Brisbane, Queensland, Australia.

出版信息

Emerg Med Australas. 2011 Aug;23(4):458-65. doi: 10.1111/j.1742-6723.2011.01418.x. Epub 2011 May 17.

Abstract

OBJECTIVE

The aim of the present study was to describe procedural sedation practices undertaken in a spectrum of Australian EDs.

METHODS

Eleven Australian EDs enrolled consecutive adult and paediatric patients between January 2006 and December 2008. Patients were included if a sedative drug was administered for an ED procedure. Data collection was prospective and used a specifically designed data collection document.

RESULTS

2623 patients were enrolled. 1581 were male (60.3%, 95% CI 58.4-62.2) and the mean patient age was 39.2 (SD 25.2) years. Reductions of fracture/dislocated shoulders (694 cases, 26.7%), wrist/forearm fractures (403, 15.5%) and tibia/fibula fractures (341, 13.1%) were the most common procedures. Procedures were supervised by consultants and registrars in 1424 (54.3%) and 1025 (39.1%) cases, respectively. Of 2413 patients with complete fasting status data, 1252 (51.9%, 95% CI 49.9-53.9) patients had consumed food or fluid in the previous 6 h. 1399 (53.3%, 95% CI 51.4-55.3) patients received pre-procedural medication. Pre-procedural morphine (894, 34.1%) exceeded fentanyl use (323, 12.3%), both as a sole agent and in combination with another agent. The principal sedatives used alone were propofol (857, 38.5%), midazolam (224, 10%) and ketamine (165, 7.4%). Ketamine and nitrous oxide were most commonly used in children with propofol, midazolam and opiates largely restricted to adults (P < 0.001). The intra-procedural use of adjunct fentanyl exceeded that of morphine (ratio 4:1).

CONCLUSIONS

Procedural sedation practice across Australian EDs is varies considerably. Procedural sedation 'best practice' guidelines, based upon the findings of the present study and the available evidence, are recommended.

摘要

目的

本研究旨在描述澳大利亚一系列急诊部实施的程序镇静实践。

方法

2006 年 1 月至 2008 年 12 月期间,11 家澳大利亚急诊部连续纳入成年和儿科患者。如果镇静药物用于急诊部程序,则纳入患者。数据收集是前瞻性的,使用了专门设计的数据收集文件。

结果

共纳入 2623 例患者。男性 1581 例(60.3%,95%CI 58.4-62.2),平均年龄 39.2(SD 25.2)岁。肩部(694 例,26.7%)、腕部/前臂(403 例,15.5%)和胫骨/腓骨(341 例,13.1%)骨折脱位复位是最常见的程序。2413 例患者中有完整禁食状态数据,1252 例(51.9%,95%CI 49.9-53.9)患者在 6 小时内进食或液体。1399 例(53.3%,95%CI 51.4-55.3)患者接受了术前用药。术前使用吗啡(894 例,34.1%)超过了芬太尼(323 例,12.3%),两者均为单独用药和联合用药。单独使用的主要镇静剂是丙泊酚(857 例,38.5%)、咪达唑仑(224 例,10%)和氯胺酮(165 例,7.4%)。氯胺酮和一氧化二氮在儿童中最常与丙泊酚、咪达唑仑和阿片类药物联合使用,而后者主要限于成人(P < 0.001)。术中辅助使用芬太尼超过了吗啡(比例为 4:1)。

结论

澳大利亚急诊部的程序镇静实践差异很大。建议根据本研究结果和现有证据制定程序镇静“最佳实践”指南。

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