各种铁补充剂对龋齿发生的体外抑龋作用。
In vitro cariostatic effects of various iron supplements on the initiation of dental caries.
作者信息
Al-Shalan Thakib A
机构信息
Department of Preventive Dental Sciences, College of Dentistry, King Saud University, P.O. Box 60169, Riyadh 11545, Saudi Arabia.
出版信息
Saudi Dent J. 2009 Oct;21(3):117-22. doi: 10.1016/j.sdentj.2009.05.001. Epub 2009 Oct 29.
UNLABELLED
Previous animal and laboratory studies have shown the possible cariostatic effect of iron. The purpose of this study was to in vitro study the effect of different concentrations of four iron supplements on the initiation of dental caries.
MATERIALS AND METHODS
Four products of iron supplements were used namely fre-in-sol, ferotonic, feromin and ferose. Two hundred extracted teeth were distributed randomly into 10 groups. Eight groups were from the four iron products in two concentrations (100% and 50%) in addition to the positive and negative control groups. Mutans streptococci bacteria (6715) grown in Todd Hewitt Broth were used. Assessment of decalcification and cavitation was done daily for 60 days.
RESULTS
It showed that different iron - supplement products play cariostatic effect in the initiation of the dental caries. With the exception of 100% and 50% ferose, both 100% and 50% concentrations of all supplements have cariostatic effect. The mean dates for decalcification varied with lowest for the positive control (12.2 days) and the highest was for 50% feromin. Cavitation was seen in the positive control and 100% ferose groups with mean on the first day of cavitation of 57 days.
CONCLUSION
It was concluded that iron may have cariostatic effect on the in vitro development of dental caries in human teeth.
未标注
先前的动物和实验室研究表明铁可能具有防龋作用。本研究的目的是在体外研究四种铁补充剂不同浓度对龋齿发生的影响。
材料与方法
使用四种铁补充剂产品，即富里索、费罗通、费罗明和费罗糖。200颗拔除的牙齿随机分为10组。除阳性和阴性对照组外，八组来自四种铁产品的两种浓度（100%和50%）。使用在托德-休伊特肉汤中生长的变形链球菌（6715）。每天评估脱矿和空洞形成情况，持续60天。
结果
结果表明，不同的铁补充剂产品在龋齿发生过程中发挥防龋作用。除100%和50%的费罗糖外，所有补充剂的100%和50%浓度均具有防龋作用。脱矿的平均日期各不相同，阳性对照组最低（12.2天），50%的费罗明最高。在阳性对照组和100%的费罗糖组中观察到空洞形成，空洞形成的平均天数为第57天。
结论
得出的结论是，铁可能对人牙齿龋齿的体外发展具有防龋作用。
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