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沙特阿拉伯和埃及缺血性心脏病患者的静息心率。

Resting heart rate in patients with ischemic heart disease in Saudi Arabia and Egypt.

作者信息

Kinsara Abdulhalim J, Najm Hani K, Anazi Menwar Al, Tamim Hani

机构信息

Department of Cardiology, King Abdulaziz Medical City, Jeddah, Saudi Arabia.

出版信息

J Saudi Heart Assoc. 2011 Oct;23(4):225-32. doi: 10.1016/j.jsha.2011.05.001. Epub 2011 May 17.

Abstract

AIM

To assess the level of resting heart rate (RHR) in an outpatient population presenting with stable coronary artery disease (CAD) as well as to measure its association with current therapeutic management strategies for cardiovascular events.

MATERIALS AND METHODS

A multi-center cross-sectional survey was carried out in Saudi Arabia and Egypt over a three month period (between January 2007 and April 2007). 2049 patients with CAD without clinical heart failure (HF) were included in this study through "cluster sampling". RHR was measured by manual palpitation.

RESULTS

Mean age of CAD patients was 56.7 ± 10.4 and the mean RHR was 78.9 ± 13.9 b/m. 1686 patients (83.1%) were on β-blockers for whom the RHR was 78.5 ± 14.0 b/m (95.5% had RHR ⩾ 60 b/m, which is higher than recommended by the guidelines). 1094 (73.5%) of patients on β-blockers were on a lower dose, probably to avoid the complications associated with such a class. Among those not on β-blockers (16.9%), RHR was 80.9 ± 13.0 b/m. Moreover, 98 patients (4.8%) were on calcium channel blocker (diltiazem or verapamil) but not on β-blockers, for whom the RHR was 80.9 ± 12.0 b/m. Finally, 163 patients (8.0%) were on both β-blockers and the calcium channel blocker, and their RHR was 79.0 ± 14.4 b/m.

CONCLUSION

Optimal target RHR has not been achieved in a significant number of screened patients. Achievements of such targets are known to decrease mortality and to improve survival.

摘要

目的

评估患有稳定型冠状动脉疾病(CAD)的门诊患者的静息心率(RHR)水平,并衡量其与当前心血管事件治疗管理策略的关联。

材料与方法

在沙特阿拉伯和埃及进行了为期三个月(2007年1月至2007年4月)的多中心横断面调查。通过“整群抽样”纳入了2049例无临床心力衰竭(HF)的CAD患者。通过手动触诊测量RHR。

结果

CAD患者的平均年龄为56.7±10.4岁,平均RHR为78.9±13.9次/分钟。1686例患者(83.1%)服用β受体阻滞剂,其RHR为78.5±14.0次/分钟(95.5%的患者RHR≥60次/分钟,高于指南推荐值)。服用β受体阻滞剂的患者中有1094例(73.5%)使用较低剂量,可能是为了避免此类药物相关的并发症。在未服用β受体阻滞剂的患者中(16.9%),RHR为80.9±13.0次/分钟。此外,98例患者(4.8%)服用钙通道阻滞剂(地尔硫䓬或维拉帕米)但未服用β受体阻滞剂,其RHR为80.9±12.0次/分钟。最后,163例患者(8.0%)同时服用β受体阻滞剂和钙通道阻滞剂,其RHR为79.0±14.4次/分钟。

结论

大量筛查患者未达到最佳目标RHR。已知实现此类目标可降低死亡率并提高生存率。

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