Hylander E, Ladefoged K, Jarnum S
Medical Dept. P, Rigshospitalet, Copenhagen, Denmark.
Scand J Gastroenterol. 1990 Jul;25(7):705-10. doi: 10.3109/00365529008997596.
Calcium absorption was studied in 62 patients with Crohn's disease during a 1-week admission on a standardized diet supplying 70 g fat, 800 mg calcium, and 200 mg oxalate. All patients had been subjected to a distal small-bowel resection of at least 50 cm. Twenty-two had an ileostomy, and 40 had at least half of the colon in function. In all patients the disease was inactive. Calcium absorption was determined by the fractional accumulation in the skeleton of the antebrachium of an intravenous and oral dose of 47Ca. Calcium absorption was significantly lower in patients with ileostomy (median, 10%; range, 5-18%) than in patients with part of or the whole colon in function (median, 14%; range, 6-22%). The present study shows that in patients with extensive small-bowel resection preservation of at least half of the colon improves calcium absorption.
对62例克罗恩病患者进行了钙吸收研究，这些患者在住院1周期间采用标准化饮食，该饮食含70克脂肪、800毫克钙和200毫克草酸盐。所有患者均接受了至少50厘米的远端小肠切除术。22例患者行回肠造口术，40例患者至少保留了一半有功能的结肠。所有患者的疾病均处于非活动期。通过静脉注射和口服剂量的47Ca在前臂骨骼中的分数积累来测定钙吸收。回肠造口术患者的钙吸收（中位数为10%；范围为5%-18%）明显低于部分或全部结肠有功能的患者（中位数为14%；范围为6%-22%）。本研究表明，在广泛小肠切除的患者中，保留至少一半的结肠可改善钙吸收。
