Zimatkina T I, Oparin D A
Ukr Biokhim Zh (1978). 1990 May-Jun;62(3):77-80.
The B1-antivitamin activity of oxythiamine disulphide monosulphoxide has been determined in experiments on albino mice. It is shown that this derivative is less toxic and exerts a more profound and prolonged inhibitory action on the pyruvate dehydrogenase and transketolase activity in the animal body in comparison with initial oxythiamine disulphide.