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[不同硫胺素氧代物给药方案下白化大鼠再生肝脏中硫胺素焦磷酸依赖性酶]

[Thiamine pyrophosphate-dependent enzymes in the regenerating liver of albino rats under different regimens of oxythiamine administration].

作者信息

Kravchuk R I

出版信息

Vopr Med Khim. 1985 Nov-Dec;31(6):104-7.

PMID:4090374
Abstract

Activities of the thiamine pyrophosphate-dependent enzymes (pyruvate dehydrogenase, oxoglutarate dehydrogenase, transketolase) were increased in regenerating rat liver tissue as compared with their activities in the intact tissue. After administration of oxythiamine (20 mg/kg, within 10 days, subcutaneously) into the animals the enzymatic activity studied was decreased.

摘要

与完整组织相比,硫胺素焦磷酸依赖性酶(丙酮酸脱氢酶、酮戊二酸脱氢酶、转酮醇酶)在再生大鼠肝组织中的活性增加。给动物皮下注射氧硫胺(20毫克/千克,持续10天)后,所研究的酶活性降低。

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Vopr Med Khim. 1985 Nov-Dec;31(6):104-7.
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