Zimatkina T I, Oparin D A, Ostrovskiĭ Iu M
Ukr Biokhim Zh (1978). 1988 Nov-Dec;60(6):43-8.
B1-antivitamin activity of symmetrical oxythiamine disulphide esters with succinic and o-phthalic acids has been studied in experiments on albino mice. It is shown that O-acyloxythiamine disulphides exert more profound and prolonged inhibitory effect on the transketolase activity in the animal body in comparison with the known antagonist of vitamin B1, oxythiamine, and the initial oxythiamine disulphide.
在对白化小鼠的实验中，研究了对称的氧硫胺二硫化物酯与琥珀酸和邻苯二甲酸的B1-抗维生素活性。结果表明，与已知的维生素B1拮抗剂氧硫胺和初始的氧硫胺二硫化物相比，O-酰氧基硫胺二硫化物对动物体内转酮醇酶活性具有更深刻和持久的抑制作用。
