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Adapting a drug screening platform to discover associations of molecular targeted radiosensitizers with genomic biomarkers.调整药物筛选平台以发现分子靶向放射增敏剂与基因组生物标志物之间的关联。
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本文引用的文献

1
Independent validation of a model using cell line chemosensitivity to predict response to therapy.使用细胞系化疗敏感性对模型进行独立验证,以预测对治疗的反应。
J Natl Cancer Inst. 2013 Sep 4;105(17):1284-91. doi: 10.1093/jnci/djt202. Epub 2013 Aug 20.
2
The clinical relevance of cancer cell lines.癌细胞系的临床相关性。
J Natl Cancer Inst. 2013 Apr 3;105(7):452-8. doi: 10.1093/jnci/djt007. Epub 2013 Feb 21.
3
Clinical medicine. Biomarker tests need closer scrutiny, IOM concludes.临床医学。美国医学研究所得出结论,生物标志物检测需要更严格的审查。
Science. 2012 Mar 30;335(6076):1554. doi: 10.1126/science.335.6076.1554.
4
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.癌症细胞系百科全书使对抗癌药物敏感性的预测建模成为可能。
Nature. 2012 Mar 28;483(7391):603-7. doi: 10.1038/nature11003.
5
Predictive and prognostic factors for non-small cell lung cancer--potholes in the road to the promised land.非小细胞肺癌的预测和预后因素——通往理想境界之路上的坑洼
J Natl Cancer Inst. 2011 Dec 21;103(24):1810-1. doi: 10.1093/jnci/djr497. Epub 2011 Dec 8.
6
What information should be required to support clinical "omics" publications?支持临床“组学”出版物需要哪些信息?
Clin Chem. 2011 May;57(5):688-90. doi: 10.1373/clinchem.2010.158618.
7
Towards patient-based cancer therapeutics.迈向基于患者的癌症治疗方法。
Nat Biotechnol. 2010 Sep;28(9):904-6. doi: 10.1038/nbt0910-904.
8
Lung cancer cell lines as tools for biomedical discovery and research.肺癌细胞系作为生物医学发现和研究的工具。
J Natl Cancer Inst. 2010 Sep 8;102(17):1310-21. doi: 10.1093/jnci/djq279. Epub 2010 Aug 2.
9
Microarrays: retracing steps.微阵列:追溯步骤。
Nat Med. 2007 Nov;13(11):1276-7; author reply 1277-8. doi: 10.1038/nm1107-1276b.
10
The NCI60 human tumour cell line anticancer drug screen.美国国立癌症研究所60种人类肿瘤细胞系抗癌药物筛选
Nat Rev Cancer. 2006 Oct;6(10):813-23. doi: 10.1038/nrc1951.

Precision medicine for cancer patients: lessons learned and the path forward.

作者信息

Gazdar Adi F, Minna John D

出版信息

J Natl Cancer Inst. 2013 Sep 4;105(17):1262-3. doi: 10.1093/jnci/djt219. Epub 2013 Aug 20.

DOI:10.1093/jnci/djt219
PMID:23964132
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3760782/
Abstract
摘要