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经内镜食管黏膜下剥离术治疗 Barrett 食管及其并发症

Radical excision of Barrett's esophagus and complete recovery of normal squamous epithelium.

机构信息

Department of Gastroenterology and Neurology, Kagawa University, Kagawa 761-0793, Japan.

出版信息

World J Gastroenterol. 2013 Aug 21;19(31):5195-8. doi: 10.3748/wjg.v19.i31.5195.

Abstract

To treat Barrett's esophagus (BE), radiofrequency ablation or cryotherapy are effective treatments for eradicating BE with dysplasia and intestinal metaplasia, and reduce the rates of Barrett's esophageal adenocarcinoma (BAC). However, patients with BE and dysplasia or early cancer who achieved complete eradication of intestinal metaplasia, BE recurred in 5% within a year, requiring expensive endoscopic surveillances. We performed endoscopic submucosal dissection as complete radically curable treatment procedure for BE with dysplasia, intestinal metaplasia and BAC.

摘要

为了治疗 Barrett 食管(BE),射频消融或冷冻疗法是有效治疗 BE 伴异型增生和肠化生的方法,可以降低 Barrett 食管腺癌(BAC)的发生率。然而,BE 伴异型增生或早期癌症患者在完全消除肠化生后,一年内仍有 5%的患者出现 BE 复发,需要昂贵的内镜监测。我们对 BE 伴异型增生、肠化生和 BAC 行内镜黏膜下剥离术,作为根治性治疗的方法。

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