食管高级别异型增生和黏膜内癌的切除术：何时及如何进行？
Esophageal resection for high-grade dysplasia and intramucosal carcinoma: When and how?
机构信息
Department of Medicine, The University of Chicago Pritzker School of Medicine, Chicago, IL 60637, United States.
出版信息
World J Gastroenterol. 2010 Aug 14;16(30):3786-92. doi: 10.3748/wjg.v16.i30.3786.
Abstract
High-grade dysplasia (HGD) and intramucosal carcinoma (IMC) in the setting of Barrett's esophagus have traditionally been treated with esophagectomy. However, with the advent of endoscopic mucosal resection and endoscopic ablative therapies, endoscopic therapy at centers with expertise is now an established treatment of Barrett's-esophagus-related neoplasia, including HGD and IMC. Esophagectomy is today reserved for more selected cases with submucosal invasion, evidence for lymph node metastasis, or unsuccessful endoscopic therapy.
摘要
高级别异型增生（HGD）和黏膜内癌（IMC）是 Barrett 食管的传统治疗方法是食管切除术。然而，随着内镜黏膜切除术和内镜消融治疗的出现，在具有专业知识的中心进行内镜治疗现在是 Barrett 食管相关肿瘤的既定治疗方法，包括 HGD 和 IMC。对于有黏膜下浸润、淋巴结转移证据或内镜治疗失败的更具选择性的病例，今天仍然保留食管切除术。
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