Magnetoencephalography Laboratory, Division of Neurosurgery, The University of Texas Medical Branch.
J Cogn Neurosci. 1990 Winter;2(1):44-50. doi: 10.1162/jocn.1990.2.1.44.
Utilizing the high spatial and temporal resolution of magnetoencephalography in conjunction with magnetic resonance images, the current study explored the underlying electrical patterns of cortical excitation during both contralateral and ipsilateral auditory stimulation. Instead of studying only the peaks of the N100 component of the evoked magnetic field, a 30-msec window was chosen about the area where the peaks occurred and the intracranial sources generating that component were estimated at successive 5-msec intervals. Results indicated that the sources for both contralateral and ipsilateral conditions were best represented as a continuous movement of activation in an anterior-inferior direction along the superior surface of the temporal lobe. Although the peak magnetic fields of the N100 to contralateral stimulation were of shorter latency and higher amplitude, the generating sources of both had very similar time-dependent movement patterns, and comparisons of source localizations were dependent on the latency at which they were contrasted.
利用脑磁图的高空间和时间分辨率，并结合磁共振图像，本研究探讨了在对侧和同侧听觉刺激期间皮质兴奋的潜在电模式。本研究没有仅研究诱发磁场的 N100 成分的峰值，而是选择了在峰值发生的区域周围约 30 毫秒的窗口，并在连续的 5 毫秒间隔内估计产生该成分的颅内源。结果表明，无论是对侧还是同侧条件，源都最好表示为沿着颞叶上表面从前向后的连续激活运动。尽管对侧刺激的 N100 峰值的潜伏期较短且幅度较高，但两者的产生源都具有非常相似的随时间变化的运动模式，并且源定位的比较取决于对比的潜伏期。
