Neurologische Universitätsklinik Wien, Austria.
J Cogn Neurosci. 1990 Fall;2(4):373-82. doi: 10.1162/jocn.1990.2.4.373.
This contribution focuses on neurophysiological correlates of the cerebral processes subserving the control of proactive interference. Event-related negative shifts of the scalp-recorded cortical steady potential (negative DC shifts) were measured in 17 right-handed normals during two tasks of paired associate learning. The control condition was a standard word pair learning task in which unrelated word pairs were presented. In the experimental condition, proactive interference was maximized by presenting very similar words and by requiring negative transfer, i.e., by having them reappear, but in different pairings. Proactive interference leads to increased anterior frontal negative DC shifts. Furthermore, centrotemporal negative DC shifts predicted subsequent cued recall performance. In spite of elaborative strategies, an effect of subsequent mnestic performance on the P300 was observed.
本研究旨在探讨大脑控制前摄干扰的神经生理相关性。在两项联想学习任务中，我们对 17 名右利手正常被试进行了头皮记录的皮质稳态电位（负直流电偏移）的事件相关负移测量。对照组为标准的单词对学习任务，其中呈现的是不相关的单词对。在实验组中，通过呈现非常相似的单词并要求负迁移（即让它们再次出现，但在不同的配对中），最大限度地增加了前摄干扰。前摄干扰导致额前负直流电偏移增加。此外，中央颞负直流电偏移预测了随后的线索回忆表现。尽管存在详尽的策略，但仍观察到后续记忆表现对 P300 的影响。
