Beard C M, Melton L J, Cedel S L, Richelson L S, Riggs B L
Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905.
J Bone Miner Res. 1990 Jul;5(7):691-9. doi: 10.1002/jbmr.5650050705.
To determine the accuracy of self-reported risk factors for osteoporosis, an age-stratified random sample of Rochester, MN, women was studied. Results from a structured face-to-face interview were compared with information documented in contemporary inpatient and outpatient health care records in the community. Using the kappa statistic to evaluate concordance of these two data sources, we found substantial agreement for a history of proximal femoral and distal forearm fractures, peptic ulcer disease, estrogen replacement therapy and oral contraceptive use, and cigarette and alcohol exposure. Moderate agreement was seen for histories of other age-related fractures, hysterectomy or oophorectomy, thyroidectomy, and use of thyroid supplements. Poor agreement was found for prior thyroid disease, gastrectomy, and corticosteroid or anticonvulsant use. This study demonstrates a need for greater attention to the quality of self-reported risk factor data in studies of bone loss and fractures.
为了确定自我报告的骨质疏松症风险因素的准确性，我们对明尼苏达州罗切斯特市的女性进行了一项按年龄分层的随机抽样研究。将结构化面对面访谈的结果与社区中当代住院和门诊医疗记录中记载的信息进行了比较。使用kappa统计量来评估这两个数据源的一致性，我们发现对于股骨近端和前臂远端骨折史、消化性溃疡疾病、雌激素替代疗法和口服避孕药使用情况以及吸烟和饮酒情况，二者有高度一致性。对于其他与年龄相关的骨折史、子宫切除术或卵巢切除术、甲状腺切除术以及甲状腺补充剂的使用情况，一致性为中等。对于既往甲状腺疾病、胃切除术以及皮质类固醇或抗惊厥药的使用情况，一致性较差。这项研究表明，在骨质流失和骨折研究中，需要更加关注自我报告的风险因素数据的质量。
