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苯二氮䓬类药物联合电抽搐治疗紧张症的疗效。

Effective treatment of catatonia by combination of benzodiazepine and electroconvulsive therapy.

机构信息

Department of Psychiatry, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey.

出版信息

J ECT. 2013 Sep;29(3):206-9. doi: 10.1097/YCT.0b013e3182887a1a.

DOI:10.1097/YCT.0b013e3182887a1a
PMID:23965606
Abstract

OBJECTIVE

Catatonia, a motor dysregulation syndrome, can emerge in numerous psychiatric disorders, mainly in schizophrenia and mood disorders, and metabolic and endocrine disorders such as infections, toxic states, epilepsy, and traumatic brain injury. In our study, we aimed to investigate demographic, clinical, and treatment-related characteristics of catatonic patients managed in our inpatient clinic.

METHODS

The medical records of 57 patients diagnosed to have catatonia according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision, criteria who were admitted to the inpatient psychiatry clinic of the Gaziantep University School of Medicine between 1 January, 2003, and 31 December, 2011, were retrospectively reviewed.

RESULTS

In patients with catatonia, mood disorders (63.2%) were found to be the most common underlying or primary disease, whereas mutism (47.4%) was found to be the most common catatonic symptom. There was a comorbid medical condition in 9 patients (15.8%). Patients underwent an average of 9.00 electroconvulsive therapy (ECT) sessions. Among 57 patients with catatonia, catatonic symptoms were resolved in 57 patients (100%) by benzodiazepine and ECT.

CONCLUSIONS

In our study, full recovery was achieved in catatonia by benzodiazepine plus ECT combination. As a result, we recommend combined ECT and benzodiazepine for catatonia.

摘要

目的

紧张症是一种运动调节障碍综合征,可出现在许多精神疾病中,主要出现在精神分裂症和心境障碍中,以及代谢和内分泌紊乱,如感染、中毒状态、癫痫和创伤性脑损伤。在我们的研究中,我们旨在调查在我们的住院诊所中管理的紧张症患者的人口统计学、临床和治疗相关特征。

方法

回顾性分析了 2003 年 1 月 1 日至 2011 年 12 月 31 日期间在加济安泰普大学医学院住院精神病诊所住院的根据《精神障碍诊断与统计手册》第 4 版,文本修订版诊断为紧张症的 57 例患者的病历。

结果

在紧张症患者中,心境障碍(63.2%)是最常见的潜在或原发性疾病,而缄默症(47.4%)是最常见的紧张症症状。9 例(15.8%)患者合并有合并症。患者平均接受 9.00 次电休克治疗(ECT)。在 57 例紧张症患者中,57 例(100%)患者通过苯二氮䓬类药物和 ECT 使紧张症症状得到缓解。

结论

在我们的研究中,苯二氮䓬类药物联合 ECT 可使紧张症完全缓解。因此,我们建议联合 ECT 和苯二氮䓬类药物治疗紧张症。

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