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[成都地区城乡0-14岁儿童哮喘的流行病学调查与分析]

[Epidemiological survey and analysis of asthma in children aged 0-14 years old in urban and rural areas of Chengdu region].

作者信息

Li Min, Zhang Qiong, Shi Wei-Juan, Li Lan, Li Yan, Pang Ying, Yao Bin, Jiang Hong

机构信息

Sichuan Academy of Medical Sciences and Sichuan Province People's Hospital, Chengdu 610072, China.

出版信息

Zhongguo Dang Dai Er Ke Za Zhi. 2013 Aug;15(8):609-13.

Abstract

OBJECTIVE

To investigate the prevalence and incidence of asthma among children aged 0-14 years, with different living environments, economic levels, and sanitary conditions, in the urban and rural areas of Chengdu, China, and their influential factors.

METHODS

Children aged 0-14 years who were selected from urban, suburban and rural areas of Chengdu, were included in the study. The subjects were selected from all children aged 0-14 years in schools, kindergartens and communities by random, cluster and non-proportional sampling. Parents were surveyed by questionnaire to find out suspected cases, which were then confirmed by inquiry and physical examination in the department of respiratory medicine. All the obtained data were analyzed using SPSS/PC statistical software.

RESULTS

A total of 12082 children from the urban areas, 5677 from suburban areas and 5590 from the rural areas were included in the study. Of all the subjects, 551 (4.56%) had confirmed asthma, 150 (2.64%) had cough variant asthma (CVA), and 142 (2.54%) had suspected asthma. The prevalence rate of asthma was significantly higher in the urban areas than in the suburban and rural areas. The correct rate of diagnosis of asthma and CVA was highest in the urban areas, followed by the suburban and rural areas. Use of antibiotics and systemic corticosteroids was most common in the rural areas, followed by the suburban and urban areas, but this pattern was reversed for use of inhaled corticosteroids and leukotriene modifier. All the results in the three areas demonstrated that sex, age, age at which the first attack occurred, respiratory tract infection, inhalation/intake of allergens and genetic factors were significantly associated with asthmatic attack.

CONCLUSIONS

Population density, living environment, medical and health resources and economic level are associated with the prevalence and treatment of asthma.

摘要

目的

调查中国成都城乡地区0 - 14岁儿童在不同生活环境、经济水平和卫生条件下哮喘的患病率和发病率及其影响因素。

方法

选取成都市区、郊区和农村地区0 - 14岁儿童纳入研究。通过随机、整群和非比例抽样从学校、幼儿园和社区的所有0 - 14岁儿童中选取研究对象。通过问卷调查家长以找出疑似病例,然后在呼吸内科通过询问和体格检查进行确诊。所有获得的数据使用SPSS/PC统计软件进行分析。

结果

共纳入12082名市区儿童、5677名郊区儿童和5590名农村儿童。在所有研究对象中,确诊哮喘的有551例(4.56%),咳嗽变异性哮喘(CVA)150例(2.64%),疑似哮喘142例(2.54%)。哮喘患病率市区显著高于郊区和农村。哮喘和CVA的诊断正确率市区最高,其次是郊区和农村。抗生素和全身用糖皮质激素的使用在农村最常见,其次是郊区和市区,但吸入性糖皮质激素和白三烯调节剂的使用情况则相反。三个地区的所有结果均表明,性别、年龄、首次发作年龄、呼吸道感染、吸入/摄入变应原和遗传因素与哮喘发作显著相关。

结论

人口密度、生活环境、医疗卫生资源和经济水平与哮喘的患病率及治疗情况相关。

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