目标明确：细胞可塑性增强肿瘤发生能力。 - Suppr

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超能文献

Poised with purpose: cell plasticity enhances tumorigenicity.

作者信息

Marjanovic Nemanja D, Weinberg Robert A, Chaffer Christine L

机构信息

Whitehead Institute for Biomedical Research; Cambridge, MA USA.

出版信息

Cell Cycle. 2013 Sep 1;12(17):2713-4. doi: 10.4161/cc.26075. Epub 2013 Aug 19.

DOI:10.4161/cc.26075

PMID:23966153

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3899180/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a05b/3899180/f8e0603a5f5f/cc-12-2713-g1.jpg

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本文引用的文献

Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity.ZEB1 启动子处的静止染色质使乳腺癌细胞具有可塑性，并增强了致瘤性。

Cell. 2013 Jul 3;154(1):61-74. doi: 10.1016/j.cell.2013.06.005.

Cancer stem cells: current status and evolving complexities.癌症干细胞：现状与不断演变的复杂性。

Cell Stem Cell. 2012 Jun 14;10(6):717-728. doi: 10.1016/j.stem.2012.05.007.

Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells.随机状态转变导致癌细胞群体中的表型平衡。

Cell. 2011 Aug 19;146(4):633-44. doi: 10.1016/j.cell.2011.07.026.

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state.正常和肿瘤非干细胞可以自发地转化为干细胞样状态。

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A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth.持续肿瘤生长需要暂时存在的慢循环黑素瘤细胞亚群。

Cell. 2010 May 14;141(4):583-94. doi: 10.1016/j.cell.2010.04.020.

The epithelial-mesenchymal transition generates cells with properties of stem cells.上皮-间质转化产生具有干细胞特性的细胞。

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