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Poised with purpose: cell plasticity enhances tumorigenicity.

作者信息

Marjanovic Nemanja D, Weinberg Robert A, Chaffer Christine L

机构信息

Whitehead Institute for Biomedical Research; Cambridge, MA USA.

出版信息

Cell Cycle. 2013 Sep 1;12(17):2713-4. doi: 10.4161/cc.26075. Epub 2013 Aug 19.

DOI:10.4161/cc.26075
PMID:23966153
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3899180/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a05b/3899180/f8e0603a5f5f/cc-12-2713-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a05b/3899180/f8e0603a5f5f/cc-12-2713-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a05b/3899180/f8e0603a5f5f/cc-12-2713-g1.jpg

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本文引用的文献

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Cell. 2013 Jul 3;154(1):61-74. doi: 10.1016/j.cell.2013.06.005.
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Cancer stem cells: current status and evolving complexities.癌症干细胞：现状与不断演变的复杂性。
Cell Stem Cell. 2012 Jun 14;10(6):717-728. doi: 10.1016/j.stem.2012.05.007.
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Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells.随机状态转变导致癌细胞群体中的表型平衡。
表观遗传沉默肿瘤抑制因子 Par-4 促进复发性乳腺癌的化疗耐药性。
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NANOMEDICINE: will it offer possibilities to overcome multiple drug resistance in cancer?纳米医学：它会为克服癌症的多重耐药性提供可能性吗？
J Nanobiotechnology. 2016 Mar 9;14:17. doi: 10.1186/s12951-016-0172-2.
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Dynamics and plasticity of the epithelial to mesenchymal transition induced by miR-200 family inhibition.由miR-200家族抑制诱导的上皮-间质转化的动力学和可塑性。
Sci Rep. 2016 Feb 18;6:21117. doi: 10.1038/srep21117.
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Cancer Stem Cells: Plasticity Works against Therapy.癌症干细胞：可塑性对治疗产生不利影响。
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Conversion to stem-cell state in response to microenvironmental cues is regulated by balance between epithelial and mesenchymal features in lung cancer cells.肺癌细胞中，响应微环境信号向干细胞状态的转变受上皮和间充质特征之间平衡的调控。
Mol Oncol. 2016 Feb;10(2):253-71. doi: 10.1016/j.molonc.2015.10.002. Epub 2015 Oct 22.
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Cancer stem cell-driven efficacy of trastuzumab (Herceptin): towards a reclassification of clinically HER2-positive breast carcinomas.曲妥珠单抗（赫赛汀）由癌症干细胞驱动的疗效：迈向对临床HER2阳性乳腺癌的重新分类
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