Sato Tatsuhiko, Emi Kazuyuki, Osawa Yui, Bando Hajime
Osaka Rosai Hospital Clinical Research Center for Occupational Sensory Organ Disability, Sakai, Japan.
Clin Ophthalmol. 2013;7:1609-14. doi: 10.2147/OPTH.S49336. Epub 2013 Aug 9.
Fundus autofluorescence studies in eyes with macular holes (MHs) have shown a hyperautofluorescent spot corresponding to the hole and a hypoautofluorescent ring corresponding to the fluid cuff surrounding the hole. The purpose of this report is to present three cases of MH with a different fundus autofluorescence pattern.
Case 1 was a 62-year-old woman who did not know the duration of the MH in her left eye. Her decimal best-corrected visual acuity (BCVA) was 0.08. The left eye had a one-half disc diameter MH with a depigmented ring surrounding the area of the fluid cuff. Fundus autofluorescence showed a hyperautofluorescent ring corresponding to the depigmented ring. After vitrectomy, fundus autofluorescence showed the same size hyperautofluorescent ring despite the decreased size of the opened MH. Case 2 was a 69-year-old woman who had been diagnosed with MH in the right eye 13 years earlier. Her decimal BCVA was 0.1. The right eye had a one-half disc diameter MH with a depigmented ring surrounding the area of the fluid cuff. Fundus autofluorescence showed a hyperautofluorescent ring corresponding to the depigmented ring. Postoperative fundus autofluorescence showed the same size hyperautofluorescent ring despite the hole being closed. The decimal BCVA was 0.2 in her right eye 6 months after vitrectomy. Case 3 was a 71-year-old woman who had been diagnosed with MH in the right eye 15 years earlier. Her decimal BCVA was 0.1. The right eye had a one-half disc diameter MH with a depigmented ring which corresponded with a hyperautofluorescent ring. Postoperative fundus autofluorescence showed the same size hyperautofluorescent ring despite the hole being closed. The decimal BCVA was 0.2 in her right eye 6 months after vitrectomy.
Our findings suggest that a hyperautofluorescent ring in eyes with MHs may be an indicator of a poor surgical prognosis both anatomically and functionally.
黄斑裂孔（MH）眼的眼底自发荧光研究显示，与裂孔对应的是高自发荧光斑，与围绕裂孔的液体袖套对应的是低自发荧光环。本报告的目的是介绍三例具有不同眼底自发荧光模式的MH病例。
病例1是一名62岁女性，她不知道左眼MH的持续时间。她的小数最佳矫正视力（BCVA）为0.08。左眼有一个直径为半个视盘的MH，在液体袖套区域周围有一个色素脱失环。眼底自发荧光显示与色素脱失环对应的高自发荧光环。玻璃体切除术后，尽管开放的MH尺寸减小，但眼底自发荧光显示相同大小的高自发荧光环。病例2是一名69岁女性，13年前被诊断为右眼MH。她的小数BCVA为0.1。右眼有一个直径为半个视盘的MH，在液体袖套区域周围有一个色素脱失环。眼底自发荧光显示与色素脱失环对应的高自发荧光环。术后眼底自发荧光显示相同大小的高自发荧光环，尽管裂孔已闭合。玻璃体切除术后6个月，她右眼的小数BCVA为0.2。病例3是一名71岁女性，15年前被诊断为右眼MH。她的小数BCVA为0.1。右眼有一个直径为半个视盘的MH，有一个与高自发荧光环相对应的色素脱失环。术后眼底自发荧光显示相同大小的高自发荧光环，尽管裂孔已闭合。玻璃体切除术后6个月，她右眼的小数BCVA为0.2。
我们的研究结果表明，MH眼中的高自发荧光环可能是解剖学和功能上手术预后不良的一个指标。
