烧伤中的肾功能障碍：综述
Renal dysfunction in burns: a review.
作者信息
Ibrahim A E, Sarhane K A, Fagan S P, Goverman J
机构信息
Department of Surgery, Division of Burns, Massachusetts General Hospital, Harvard Medical School; Boston, Massachusetts, USA.
出版信息
Ann Burns Fire Disasters. 2013 Mar 31;26(1):16-25.
Abstract
Acute kidney injury (AKI), although rare, is a major complication of burn injury that commonly leads to mortality. It results from a complex interplay of various cellular and neuro-humoral changes affecting burn patients. Guidelines for the treatment of this entity are still not well defined; therefore, prevention and early diagnosis are key to avoid the unfavorable prognosis of AKI. These entail a comprehensive understanding of the global physiologic changes underlying the condition of burn patients and a judicious interpretation of their continuous homeostatic alterations. The aim of this review is to present the salient features in burn patient physiology that contribute to AKI. Strategies for identifying early AKI are presented. Finally, the different treatment modalities are revisited.
摘要
急性肾损伤（AKI）虽然罕见，但却是烧伤的主要并发症，常导致死亡。它是由影响烧伤患者的各种细胞和神经体液变化的复杂相互作用引起的。该病症的治疗指南仍未明确界定；因此，预防和早期诊断是避免AKI不良预后的关键。这需要全面了解烧伤患者病情背后的整体生理变化，并明智地解读其持续的内环境稳态改变。本综述的目的是介绍烧伤患者生理中导致AKI的显著特征。还介绍了识别早期AKI的策略。最后，回顾了不同的治疗方式。
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