Yokota Kenji, Kita Masahide, Okada Hiroyuki, Matsushita Osamu, Oguma Keiji
Graduate School of Health Science, Okayama University.
Nihon Rinsho. 2013 Aug;71(8):1374-9.
Since discovery of Helicobacter pylori, more than 30 species non-H. pylori Helicobacter spp. (NHPH) have been reported. Those NHPH were now classified into gastric Helicobacter spp. and enterohepatic Helicobacter spp.(EHS). Gastric NHPH show tight spiral and long shape in the gastric mucosa, and we can distinguish from H. pylori by light microscope. Some gastric NHPH may be zoonosis and cause gastritis in human. H. hepaticus and H. cinaedi belongs in EHS were detected in human diseases. H. hepaticus may be associated with hepatobiliary diseases in humans. Surprisingly, it was reported that H. cinaedi infection was associated with atrial arrhythmias and atherosclerosis. Many NHPH will be recognized as human pathogen in the future.
自幽门螺杆菌被发现以来,已报告了30多种非幽门螺杆菌属的螺杆菌(NHPH)。这些NHPH目前被分为胃螺杆菌属和肝肠螺杆菌属(EHS)。胃NHPH在胃黏膜中呈紧密螺旋状且形态较长,我们可以通过光学显微镜将其与幽门螺杆菌区分开来。一些胃NHPH可能是人畜共患病原体并可导致人类胃炎。在人类疾病中检测到属于EHS的肝螺杆菌和辛内氏螺杆菌。肝螺杆菌可能与人类的肝胆疾病有关。令人惊讶的是,有报道称辛内氏螺杆菌感染与房性心律失常和动脉粥样硬化有关。未来许多NHPH将被认定为人类病原体。