Brouwer A J, Groenendaal F, Han K S, de Vries L S
a Departments of Neonatology and.
b Department of Neurosurgery , Wilhelmina Children's Hospital, University Medical Centre Utrecht , Utrecht , The Netherlands.
J Matern Fetal Neonatal Med. 2015 Nov;28 Suppl 1:2273-9. doi: 10.3109/14767058.2013.796167. Epub 2013 Aug 23.
To describe our experience with a cohort of 295 infants with progressive ventricular dilatation occurring in the antenatal or neonatal period.
A search was performed in our cranial ultrasound database. All records and images of infants in whom an imaging diagnosis of progressive ventricular dilatation had been made were retrieved. In addition, modes of treatment were analysed.
Between February 1991 and March 2012, 295 neonates were admitted to our level 3 neonatal intensive care unit (NICU), and developed progressive ventricular dilatation for which they required intervention. In the majority of these infants, progressive ventricular dilatation developed following IVH grade III or IV (240/295; 81%) of whom 214/240 (89%) were preterms. Temporary treatment with lumbar punctures and punctures from ventricular reservoirs was sufficient for the majority of the preterms. A ventricular reservoir was inserted in 216/295 infants (73%). The overall infection rate was low (6%). A ventriculoperitoneal shunt (VP shunt) was inserted in 32% of the whole cohort, revision within 3 months was necessary in 20%, and shunt-related infection occurred in 12%.
This large, single-centre cohort study reports the management of progressive ventricular dilatation in newborn infants. We have shown that with our approach, complications stay within acceptable limits.
描述我们对295例在产前或新生儿期出现进行性脑室扩张的婴儿的治疗经验。
在我们的颅脑超声数据库中进行检索。检索所有已做出进行性脑室扩张影像学诊断的婴儿的记录和图像。此外，分析治疗方式。
1991年2月至2012年3月期间，295例新生儿入住我们的三级新生儿重症监护病房（NICU），并出现进行性脑室扩张，为此他们需要进行干预。在这些婴儿中，大多数进行性脑室扩张是在III级或IV级脑室内出血（IVH）后发生的（240/295；81%），其中214/240（89%）为早产儿。对于大多数早产儿，通过腰椎穿刺和脑室储液囊穿刺进行临时治疗就足够了。216/295例婴儿（73%）插入了脑室储液囊。总体感染率较低（6%）。整个队列中有32%的婴儿插入了脑室腹腔分流术（VP分流术），20%的婴儿在3个月内需要进行修复，12%的婴儿发生了与分流相关的感染。
这项大型单中心队列研究报告了新生儿进行性脑室扩张的管理情况。我们已经表明，采用我们的方法，并发症在可接受的范围内。
