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口服皮质类固醇对系统性红斑狼疮患者骨密度影响的评估：一项双能X线吸收法的初步研究

Assessment of the effect of oral corticosteroids on bone mineral density in systemic lupus erythematosus: a preliminary study with dual energy x ray absorptiometry.

作者信息

Dhillon V B, Davies M C, Hall M L, Round J M, Ell P J, Jacobs H S, Snaith M L, Isenberg D A

机构信息

Department of Rheumatology Research, University College and Middlesex School of Medicine, London.

出版信息

Ann Rheum Dis. 1990 Aug;49(8):624-6. doi: 10.1136/ard.49.8.624.

DOI:10.1136/ard.49.8.624
PMID:2396869
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1004178/
Abstract

Dual energy x ray absorptiometry and a wide range of blood and urine tests were used to assess the propensity of patients with systemic lupus erythematosus to develop an impairment of bone mineral density. Surprisingly, in this preliminary study no significant differences in bone mineral density were found when patients taking 10 mg or more of prednisolone for six months or longer were compared with those who had never taken prednisolone.

摘要

采用双能X线吸收测定法以及一系列血液和尿液检测，来评估系统性红斑狼疮患者发生骨密度损害的倾向。令人惊讶的是，在这项初步研究中，将服用泼尼松龙10毫克或更多剂量达六个月或更长时间的患者与从未服用过泼尼松龙的患者相比较时，未发现骨密度有显著差异。

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Systemic lupus erythematosus--survival patterns. Experience with 609 patients.系统性红斑狼疮——生存模式。609例患者的经验。
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