Pierce W S, Rosenberg G, Snyder A J, Pae W E, Donachy J H, Waldhausen J A
Department of Surgery, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey 17033.
Ann Surg. 1990 Sep;212(3):339-43; discussion 343-4. doi: 10.1097/00000658-199009000-00012.
Advances in microelectronics, high-strength magnets, and control system design now make replacement of the heart using an implantable, electrically powered pump feasible. The device described herein is a compact, dual pusher plate unit with valved polyurethane sac-type ventricles positioned at either end. The power unit consists of a small, brushless direct current motor and a motion translator. A microprocessor control system is used to regulate heart beat rate and provide left-right output balance. Bench studies lasting for as long as 1 year have been performed. Heart replacement with the electric heart has been performed in 18 calves since 1984. The longest survivor lived for more than 7 months. Among the causes of termination were component failure, thromboembolic complications, and bleeding. No major problem has been identified that precludes prolonged use of the electric heart. In the future the patient with end-stage heart disease will have an electric artificial heart as one therapeutic option.
微电子技术、高强度磁体和控制系统设计的进步，使得使用可植入式电动泵替代心脏成为可能。本文所述的装置是一个紧凑的双推板单元，两端各有一个带瓣膜的聚氨酯囊式心室。动力单元由一个小型无刷直流电机和一个运动转换器组成。微处理器控制系统用于调节心率并提供左右输出平衡。已经进行了长达1年的实验台研究。自1984年以来，已经在18头小牛身上进行了电动心脏置换手术。存活时间最长的小牛活了7个多月。终止实验的原因包括部件故障、血栓栓塞并发症和出血。尚未发现有任何重大问题会妨碍电动心脏的长期使用。未来，终末期心脏病患者将有电动人工心脏这一治疗选择。
