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[遗传性动脉高血压大鼠的内分泌与淋巴关系]

[Endocrine and lymphoid interrelations in rats with hereditary arterial hypertension].

作者信息

Shorin Iu P, Sedova L A, Seliatitskaia V G, Markel' A L

出版信息

Arkh Anat Gistol Embriol. 1990 Apr;98(4):57-61.

PMID:2396908
Abstract

Functional state of the adrenals and structural organization of the thymus and lymph nodes in the rats with hereditary stress-induced arterial hypertension (HSIAH) have been investigated in the control and against the background of a prolonged staying under conditions of a moderate cold. In comparison with the initial population of Wistar rats, the test animals demonstrate an elevated level of corticosterone, decreased mass and size of the thymus, the size of the popliteal lymph nodes is increased at the expense of the structural components of the medulla. In 7 weeks of living in cold secretion of adrenal steroids in Wistar rats increases greatly and it is noticeably less in the HSIAH rats. Structural changes in the thymus are also insignificant, but reaction of the lymph nodes is important. Their size sharply diminishes at the expense of certain structural components of the medulla. A shift towards mature forms of the plasmocytic line cells takes place.

摘要

对遗传性应激诱导性动脉高血压(HSIAH)大鼠的肾上腺功能状态以及胸腺和淋巴结的结构组织进行了研究,研究分为对照组以及在中度寒冷条件下长期停留的背景组。与初始的Wistar大鼠群体相比,受试动物表现出皮质酮水平升高、胸腺质量和大小减小、腘淋巴结大小增加,且增加是由髓质的结构成分所致。在寒冷环境中生活7周后,Wistar大鼠肾上腺类固醇的分泌大幅增加,而HSIAH大鼠的分泌则明显较少。胸腺的结构变化也不显著,但淋巴结的反应很重要。其大小急剧减小,减小是由髓质的某些结构成分所致。浆细胞系细胞向成熟形式转变。

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