From the Twin Cities Spine Center, Minneapolis, MN.
Spine (Phila Pa 1976). 2013 Dec 1;38(25):E1616-23. doi: 10.1097/BRS.0b013e3182a8c3b7.
Retrospective cohort study.
The fusion risk score (FRS) is introduced to assess baseline risk of spine fusion surgery preoperatively. An objective method of stratifying risk allows the surgeon to control risk through tailoring intervention and explain differences in complication profile in high-complexity practice.
Research has identified an elevated risk of serious complications in performing spine fusion surgery in the elderly, yet the rate of such surgery continues to increase. A range of comorbidities and the surgical factors are demonstrated predictors of perioperative risk.
Retrospective review was made of 364 consecutive fusion surgical procedures in patients older than 65 years in an 18-month period. Logistic regression analysis was performed to identify factors predictive for the occurrence of perioperative events. The predictive variables were incorporated in a weighted fashion into the FRS scaled from 1 to 20. Patient demographics and comorbidities were incorporated into the FRS patient score (maximum 10) and surgical approach, levels, and osteotomies into the FRS procedure score (maximum 10).
Multivariate analysis demonstrated chronic kidney disease (odds ratio [OR] = 5.3, 95% confidence interval [CI]: 1.5-18.6, P = 0.008), chronic obstructive pulmonary disease (OR = 5.3, 95% CI: 2.0-14.2, P < 0.001), ischemic heart disease (OR = 4.1, 95% CI: 2.0-8.4, P < 0.001), an open anterior approach (OR = 3.6, 95% CI: 1.4-9.3, P = 0.010), diabetes (OR = 3.0, 95% CI: 1.4-6.4, P = 0.004), previous spinal surgery at the same site (OR = 2.6, 95% CI: 1.3-4.9, P = 0.005), age (OR = 1.07, 95% CI: 1.01-1.13, P = 0.019), and the number of motion segments fused (P = 0.049) to be predictive of perioperative events. When applied, the FRS was highly predictive of perioperative events, intensive care unit admission, operative time, blood loss, and length of stay (all P < 0.0001). A score over threshold 9 carries a greater than 50% risk of perioperative events.
The FRS predicts the risk of complications after spine fusion surgery on the basis of patient and surgery characteristics. It also predicts the risk of intensive care unit admission and correlates with operative time, blood loss, and postoperative length of stay. By balancing the FRS procedure score to the individual FRS patient score, the surgeon can quantify and control perioperative risk.
回顾性队列研究。
融合风险评分(FRS)用于术前评估脊柱融合手术的基线风险。客观的风险分层方法允许外科医生通过调整干预措施来控制风险,并解释在高复杂度实践中并发症谱的差异。
研究已经确定在老年人中进行脊柱融合手术存在严重并发症的风险增加,但此类手术的比例仍在继续增加。一系列合并症和手术因素被证明是围手术期风险的预测因素。
对 18 个月内 65 岁以上患者的 364 例连续融合手术进行回顾性分析。进行逻辑回归分析以确定预测围手术期事件发生的因素。将预测变量以加权方式纳入评分范围为 1 至 20 的 FRS 中。患者的人口统计学和合并症被纳入 FRS 患者评分(最高 10 分),手术方法、水平和截骨术被纳入 FRS 手术评分(最高 10 分)。
多变量分析表明慢性肾脏病(优势比 [OR] = 5.3,95%置信区间 [CI]:1.5-18.6,P = 0.008)、慢性阻塞性肺疾病(OR = 5.3,95% CI:2.0-14.2,P < 0.001)、缺血性心脏病(OR = 4.1,95% CI:2.0-8.4,P < 0.001)、开放前路(OR = 3.6,95% CI:1.4-9.3,P = 0.010)、糖尿病(OR = 3.0,95% CI:1.4-6.4,P = 0.004)、同一部位先前的脊柱手术(OR = 2.6,95% CI:1.3-4.9,P = 0.005)、年龄(OR = 1.07,95% CI:1.01-1.13,P = 0.019)和融合的运动节段数量(P = 0.049)与围手术期事件相关。应用时,FRS 高度预测围手术期事件、重症监护病房入院、手术时间、失血量和住院时间(均 P < 0.0001)。评分超过阈值 9 时,围手术期事件的风险大于 50%。
FRS 根据患者和手术特征预测脊柱融合手术后并发症的风险。它还预测重症监护病房入院的风险,并与手术时间、失血量和术后住院时间相关。通过平衡 FRS 手术评分和个体 FRS 患者评分,外科医生可以量化和控制围手术期风险。