Kelly Jason P, Alcala-Marquez Christopher, Dawson John M, Mehbod Amir A, Pinto Manuel R
Twin Cities Spine Center, Minneapolis, MN, USA.
J Spine Surg. 2019 Sep;5(3):351-357. doi: 10.21037/jss.2019.08.09.
The purpose of this study was to compare outcomes of patients with degenerative spondylolisthesis treated by posterolateral lumbar fusion (PLF) versus PLF with transforaminal lumbar interbody fusion (PLF + TLIF). Studies of PLF versus PLF + TLIF have shown either equivalence or support for PLF + TLIF in lumbar spine surgery. Many are heterogeneous in the conditions treated, with few considering only spondylolisthesis of degenerative origin. Radiographic outcomes tend to favor PLF + TLIF, but this has not translated into better clinical outcomes.
This was a retrospective cohort study. Forty-nine patients undergoing single-level PLF and seventy patients undergoing single-level PLF + TLIF with two-year follow-up were retrospectively reviewed. Demographics, Oswestry Disability Index (ODI), implant cost, surgical data, and complications were analyzed.
There was no difference in ODI improvement at two-year follow-up between the cohorts (P=0.97). Dural tears were more common in the PLF cohort (P<0.01), but otherwise complication and reoperation rates were similar. Implant cost (P<0.01) and operative time (P=0.01) were higher in the PLF + TLIF cohort.
The addition of a TLIF to a PLF did not result in a functional improvement in the treatment of degenerative spondylolisthesis as measured by the ODI.
本研究旨在比较经后路腰椎融合术(PLF)与经椎间孔腰椎椎体间融合术联合后路腰椎融合术(PLF+TLIF)治疗退变性腰椎滑脱症患者的疗效。关于PLF与PLF+TLIF的研究表明,在腰椎手术中二者疗效相当或支持PLF+TLIF。许多研究在治疗的疾病方面存在异质性,很少有研究仅考虑退变性腰椎滑脱症。影像学结果倾向于支持PLF+TLIF,但这并未转化为更好的临床疗效。
这是一项回顾性队列研究。对49例行单节段PLF和70例行单节段PLF+TLIF且随访两年的患者进行回顾性分析。分析人口统计学资料、奥斯威斯利功能障碍指数(ODI)、植入物成本、手术数据和并发症。
两组在两年随访时ODI改善情况无差异(P=0.97)。硬脊膜撕裂在PLF组更常见(P<0.01),但其他方面并发症和再次手术率相似。PLF+TLIF组的植入物成本(P<0.01)和手术时间(P=0.01)更高。
根据ODI测量,在PLF基础上加做TLIF在治疗退变性腰椎滑脱症时并未带来功能改善。