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成人特发性脊柱侧凸翻修手术的风险:25年517例病例的生存分析

Risk of revision surgery for adult idiopathic scoliosis: a survival analysis of 517 cases over 25 years.

作者信息

Riouallon Guillaume, Bouyer Benjamin, Wolff Stéphane

机构信息

Groupe Hospitalier Paris Saint-Joseph, 185, rue Raymond Losserand, 75014, Paris, France.

出版信息

Eur Spine J. 2016 Aug;25(8):2527-34. doi: 10.1007/s00586-016-4505-5. Epub 2016 Mar 10.

Abstract

PURPOSE

Little is known about the long-term status of patients operated for spine deformities. The aim of this study was to determine the survival of primary fusion in adult idiopathic scoliosis and identify the risk factors of revision surgery.

METHODS

Adult patients who underwent primary fusion for idiopathic scoliosis between 1983 and 2011 were included in a continuous monocentric retrospective series. Any additional surgery was registered for survival analysis. Survival and follow-up were estimated by the Kaplan-Meier method and an analysis was performed to identify the risk factors of revision surgery.

RESULTS

This series included 447 women (86.5 %) and 70 men (13.5 %) reviewed after a mean follow-up of 7 years (range 0-26.4). Mean age was 44.4 years. Fusion was performed on a median 11 levels (range 3-15); revision rate was 13 % (CI 10-17), 18 % (CI 14-23) and 20 % (CI 16-26) at 5, 10 and 15 years, respectively. Revision surgery was associated with age, anterior release, length of fusion, the inferior limit of fusion, post-operative sagittal balance and junctional kyphosis. The length of fusion (HR 1.13 per vertebrae fused, p = 0.007) and the lower limit of fusion (HR 5.9, p < 0.001) remained independent predictors of revision surgery on multivariate analysis.

CONCLUSION

This series evaluated the risk of revision surgery following spinal fusion for idiopathic scoliosis. Our results show that the risk seemed to increase linearly with a rate of nearly 20 % after 10 years. The length and lower limit of fusion are the main risk factors for revision surgery. Level IV (e.g. case series).

摘要

目的

对于接受脊柱畸形手术患者的长期状况了解甚少。本研究旨在确定成人特发性脊柱侧凸初次融合的生存率,并确定翻修手术的风险因素。

方法

纳入1983年至2011年间因特发性脊柱侧凸接受初次融合手术的成年患者,形成一个连续的单中心回顾性系列。记录任何额外的手术用于生存分析。采用Kaplan-Meier法估计生存率和随访情况,并进行分析以确定翻修手术的风险因素。

结果

该系列包括447名女性(86.5%)和70名男性(13.5%),平均随访7年(范围0 - 26.4年)后进行评估。平均年龄为44.4岁。融合手术的节段中位数为11个(范围3 - 15个);5年、10年和15年时的翻修率分别为13%(可信区间10 - 17)、18%(可信区间14 - 23)和20%(可信区间16 - 26)。翻修手术与年龄、前路松解、融合长度、融合下限、术后矢状面平衡和交界性后凸有关。在多变量分析中,融合长度(每融合一个椎体的风险比为1.13,p = 0.007)和融合下限(风险比为5.9,p < 0.001)仍然是翻修手术的独立预测因素。

结论

本系列评估了特发性脊柱侧凸脊柱融合术后翻修手术的风险。我们的结果表明,风险似乎呈线性增加,10年后接近20%。融合长度和下限是翻修手术的主要风险因素。IV级(如病例系列)。

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